Table 1 Clinical characteristics of subjects according to worsening characteristicsbetween initial and follow-up CT scan
From: Antiplatelet therapy and the outcome of subjects with intracranial injury: the Italian SIMEU study
| Â | Worsening (Number = 201) | Stable/Improved (Number = 1.357) | OR (95% CI) | P value |
|---|---|---|---|---|
Sex (males) | 125 (62.2%) | 786 (57.9%) | 1.19 (0.88 to1.62) | 0.283 |
Age (mean: SD) | 65 (22) | 65 (21) | -- | -- |
Mechanism of Injury | Â | Â | Â | Â |
   Road accident | 60 (29.9%) | 414 (30.5%) | 0.97 (0.70 to 1.34) | 0.870 |
   Other causes | 86 (42.8%) | 622 (45.8%) | Reference | -- |
Glasgow Coma Scale | Â | Â | Â | Â |
   Moderate-Severe (≤ 13) | 127 (63.2%) | 308 (22.7%) | 5.84 (4.27 to 8.00) | < 0.001 |
   Mild (15 to 14) | 74 (36.8%) | 1.049 (77.3%) | Reference | -- |
Basal skull fracture | 28 (13.9%) | 117 (8.6%) | 1.71 (1.10 to 2.67) | 0.019 |
Type of lesion | Â | Â | Â | Â |
   Subdural hematoma | 106 (52.7%) | 498 (36.7%) | 1.92 (1.43 to 2.59) | < 0.001 |
   Epidural hematoma | 28 (13.9%) | 129 (9.5%) | 1.54 (0.99 to 2.39) | 0.059 |
   Intracerebral hemorrhage/contusion | 116 (57.7%) | 650 (47.9%) | 1.48 (1.10 to 2.0) | 0.010 |
   Traumatic subarachnoid hemorrhage | 105 (52.2%) | 671 (49.4%) | 1.12 (0.83 to 1.50) | 0.497 |
   Intraventricular hemorrhage | 10 (4.9%) | 84 (6.2%) | 0.79 (0.40 to 1.55) | 0.634 |
   Depressed skull fracture | 25 (12.4%) | 116 (8.5%) | 1.52 (0.96 to 2.41) | 0.086 |
Anticoagulant therapy | 18 (9.0%) | 108 (8.0%) | 1.14 (0.68 to 1.92) | 0.582 |
Antiplatelet therapy | 106 (52.7%) | 431 (31.8%) | 2.40 (1.78 to 3.23) | < 0.001 |