Figure 5
From: n-3 fatty acids, γ-linolenic acid, and antioxidants in sepsis
Biosynthesis of neuroprotectin D 1 from docosahexaenoic acid. Docosahexaenoic acid (DHA) released from the cell membrane undergoes lipoxygenation and is then followed by epoxidation and hydrolysis to generate neuroprotectin D1 (or, simply, protectin D1).