Table 5 Logistic regression analysis with ICU mortality as the dependent variable inpatients with severe sepsis

Age (per year)

1.03 (1.02 to 1.05)

< 0.001

1.03 (1 to 1.059)

0.016

Sex (female)

2.01 (1.20 to 3.37)

0.008

2.23 (1.17 to 4.24)

0.014

Comorbidities

   Diabetes mellitus

0.79 (0.43 to 1.45)

0.465

   Renal failure (with dialysis)

0.21 (0.07 to 0.64)

0.006

2.9 (0.68 to 12.45)

0.151

   Renal failure (without dialysis)

1.05 (0.52 to 2.15)

0.887

   Heart failure (NYHA III to IV)

0.96 (0.42 to 2.19)

0.929

   COPD

0.50 (0.19 to 1.28)

0.147

1.75 80.58 to 5.32)

0.319

SAPS II (per point)

1.04 (1.03 to 1.06)

< 0.001

1.03 (1.01 to 1.05)

0.002

Type of admission

   Elective surgery

R

NA

R

NA

   Emergency surgery

1.56 (0.64 to 3.84)

0.330

1.09 (0.38 to 3.5)

0.891

   Medical admission

2.28 (0.95 to 5.43)

0.064

1.7 (0.5 to 5.76)

0.392

Initial SOFA subscores

   SOFA respiratory

1.53 (1.21 to 1.92)

< 0.001

1.65 (1.24 to 2.2)

0.001

   SOFA hepatologic

1.18 (0.96 to 1.45)

0.110

1.25 (0.94 to 1.66)

0.126

   SOFA hematologic

1.32 (1.08 to 1.60)

0.006

1.28 (0.99 to 1.65)

0.059

   SOFA renal

1.29 (1.07 to 1.54)

0.006

0.92 (0.71 to 1.19)

0.535

   SOFA neurologic

1.097 (0.94 to 1.29)

0.257

   SOFA cardiovascular

1.272 (1.09 to 1.49)

0.003

1.24 (1.02 to 1.51)

0.034

Referring facility

   Other hospital

R

NA

R

NA

   Surgical ward

0.2 (0.09 to 0.45)

< 0.001

5.17 (1.2 to 22.29)

0.027

   Emergency department

0.93 (0.28 to 3.1)

0.913

3.53 (1.52 to 8.21)

0.003

   Medical ward

0.52 (0.26 to 1.05)

0.068

1.43 (0.52 to 3.93)

0.492

   Other ICU

0.31 (0.15 to 0.63)

0.001

4.87 (1.85 to 12.85)

0.001

Source of infection

   Pulmonary

0.926 (0.586 to 1.465)

0.743

   Abdominal

0.542 (0.338 to 0.871)

0.011

2.51 (1.15 to 5.44)

0.02

   Renal

1.697 (0.640 to 4.501)

0.288

   Central nervous system

0.833 (0.219 to 3.164)

0.789

   Bone

3.185 (0.328 to 30.965)

0.318

   Soft tissue

1.208 (0.427 to 3.417)

0.722