Table 1 Baseline clinical data from all patients
From: Prediction of invasive candidal infection in critically ill patients with severeacute pancreatitis
| Â | All patients | Patients without invasive candidal infection | Patients with invasive candidal infection | P value |
|---|---|---|---|---|
Number of patients (%) | 101 | 83 (82.2) | 18 (17.8) | Â |
Age, years (median, IQR)) | 60 (50 to 73) | 60 (50-72) | 62.5 (44.75 to 76.25) | 0.884 |
Median LOS ICU (days, IQR, range) | 8.9 (3.5 to 17.3, 0.1 to 53.1) | 7.3 (3.1 to 14.7, 0.1 to 53.2) | 16.9 (9.4 to 23.0, 2.2 to 53.1)a | 0.004 |
Male gender (%) | 58 (57.4) | 48 (57.8) | 10 (55.6) | 0.999 |
Median hospital LOS prior to ICU (days, IQR, range) | 4 (1 to 12, 0 to 110) | 4 (1 to 12, 0 to 110) | 4.5 (2 to 13, 0 to 17) | 0.125 |
APACHE II (median, IQR) | 16 (12 to 21) | 16 (12 to 20.5) | 17 (15 to 21.75) | 0.445 |
Mortality, ICU number (%) | 18 (17.8) | 13 (15.7) | 5 (27.8) | 0.305 |
Hospital number (%) | 30 (29.7) | 20 (24.1) | 10 (55.6)a | 0.020 |
Surgery, number (%) | 29 (28.7) | 22 (26.5) | 7 (38.9) | 0.389 |
Severe sepsis, number (%) | 37 (36.6) | 30 (36.1) | 7 (38.9) | 0.999 |
Significant pancreatic necrosis, number (%) | 53 (52.5) | 40 (48.2) | 13 (72.2) | 0.063 |
Pancreatic intervention, number (%) | MIRPN 27 (26.7) | 23 (27.7) | 4 (22.2) | 0.774 |
| Â | Open necrosectomy 18 (17.8) | 11 (13.3) | 7 (38.9)a | 0.017 |
| Â | Radiologically-guided drain 5 (5) | 4 (4.8) | 1 (5.6) | 0.999 |
| Â | Unknown 7 (6.9) | 6 (7.2) | 1 (5.6) | 0.999 |
| Â | No intervention 44 (44) | 39 (47) | 5 (27.8) | 0.191 |
Screened for colonisation with candida, number (%) | 95 (94.1) | 77 (92.8) | 18 (100) | 0.588 |
Total body sites screened | 340 | 269 | 71 | Â |
Total sites positive for Candida | 107 | 67 | 40 | Â |
Proportion of sites positive to sites screened | 0.31 | 0.25 | 0.56 | Â |
Aetiology number (%) | Gallstones 45 (44.6) | 38 (45.8) | 7 (38.9) | 0.794 |
| Â | Alcohol 30 (29.7) | 25 (30.1) | 5 (27.8) | 0.999 |
| Â | Drugs 1 (1) | 0 (0) | 1 (5.6) | 0.178 |
| Â | Other 10 (9.9) | 7 (8.4) | 3 (16.7) | 0.378 |
| Â | Idiopathic 3 (3.0) | 2 (2.4) | 1 (5.6) | 0.081 |
| Â | Unknown 12 (11.9) | 10 (12) | 2 (11.1) | 0.999 |