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Table 2 Comparison of median concentrations of blood markers between favorable and poor outcome groups

From: Predictive value of circulating interleukin-6 and heart-type fatty acid binding protein for three months clinical outcome in acute cerebral infarction: multiple blood markers profiling study

  All
(number = 175)
Favorable
(number = 111)
Poor
(number = 64)
P a
Neuronal     
   NSE (ng/ml) 6.5 (1.9 to 10.8) 5.6 (1.6 to 10.3) 7.7 (3.0 to 11.5) 0.14
   Ngb (ng/ml) 0.0 (0.0 to 2.7) 0.0 (0.0 to 0.9) 0.3 (0.0 to 9.7) < 0.001
   hFABP (ng/ml) 10.0 (6.2 to 16.3) 8.4 (5.5 to 11.9) 16.3 (9.9 to 29.7) < 0.001
   VSNL-1 (%)b 12 (6.9) 7 (6.3) 5 (7.8) 0.95
Astroglial     
   S100B (pg/ml) 31.9 (0.0 - 124.9) 20.0 (0 to 60.3) 135.2 (40.0 to 344.6) < 0.001
   GFAP (%)b 50 (28.6) 23 (20.7) 27 (42.2) 0.004
Inflammatory     
   IL-6 (pg/ml) 4.6 (0.9 to 13.0) 2.2 (0.6 to 5.5) 12.1 (6.7 to 48.0) < 0.001
   MMP-9 (ng/ml) 65.4 (30.9 to 124.1) 45.7 (21.9 to 79.5) 120.5 (61.8 to 228.3) < 0.001
   TNF-α (pg/ml) 2.3 (0.0 to 8.9) 1.3 (0.0 to 8.0) 3.3 (0.0 to 10.4) 0.22
   CRP (mg/dl) 0.26 (0.09 to 0.94) 0.19 (0.06 to 0.36) 0.87 (0.18 to 4.40) < 0.001
Haemostatic     
   PAI-1 (ng/ml) 11.1 (4.5 to 21.8) 10.3 (4.2 to 23.1) 11.5 (5.9 to 20.9) 0.57
   D-dimer (ng/ml) 521 (368 to 1083) 466 (355 to 933) 938 (450 to 1629) 0.001
  1. aStatistical analysis conducted by the Mann-Whitney U test; bCategorical variables. Values in round brackets indicate interquartile range. CRP, C-reactive protein; GFAP, glial fibrillary acidic protein; hFABP, heart type fatty acid binding protein; MMP-9 matrix metalloproteinase-9; Ngb, neuroglobin; NSE, neuron-specific enolase; PAI-1, plasminogen activator inhibitor-1; VSNL-1, visinin-like protein 1.