Neuromuscular blocking agents in acute respiratory distress syndrome: a systematic review and meta-analysis of randomized controlled trials

Table 4 Subgroup analyses for hospital mortality outcome

Subgroup	Number of patients (n)	Relative risk (95% CI)	P value (interaction between groups)
Methodologic quality of trials
Low risk of bias	339	0.78 (0.59 to 1.03)	0.38
High/unclear risk of bias	92	0.63 (0.43 to 0.92)
Cause of ARDS
Sepsis	311	0.72 (0.54 to 0.94)	0.83
Other causes	120	0.76 (0.47 to 1.24)
PaO₂/FiO₂
≥ 100 to 200	256	0.77 (0.57 to 1.03)	0.87
< 100	175	0.74 (0.51 to 1.06)

ARDS, acute respiratory distress syndrome; PaO₂/FiO₂, ratio of partial arterial pressure of oxygen to fraction of inspired oxygen.

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