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Table 4 Subgroup analyses for hospital mortality outcome

From: Neuromuscular blocking agents in acute respiratory distress syndrome: a systematic review and meta-analysis of randomized controlled trials

Subgroup Number of patients (n) Relative risk (95% CI) P value (interaction between groups)
Methodologic quality of trials    
   Low risk of bias 339 0.78 (0.59 to 1.03) 0.38
   High/unclear risk of bias 92 0.63 (0.43 to 0.92)  
Cause of ARDS    
   Sepsis 311 0.72 (0.54 to 0.94) 0.83
   Other causes 120 0.76 (0.47 to 1.24)  
PaO2/FiO2    
   ≥ 100 to 200 256 0.77 (0.57 to 1.03) 0.87
   < 100 175 0.74 (0.51 to 1.06)  
  1. ARDS, acute respiratory distress syndrome; PaO2/FiO2, ratio of partial arterial pressure of oxygen to fraction of inspired oxygen.