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Table 2 Methodologic quality of trials

From: Neuromuscular blocking agents in acute respiratory distress syndrome: a systematic review and meta-analysis of randomized controlled trials

Study

Sequence generation

Allocation concealment

Blinding

Withdrawal; loss to follow-up

Selective outcome reporting

Free of other bias

Overall risk of bias

Gainnier 2004 [12]

Low risk of bias

Low risk of bias

High risk of bias

Low risk of bias

Low risk of bias

Low risk. of bias

High

 

Computer-generated random number sequences

Centralized

Nurses aware of assignment; infusion covered by sheet

None

None

None

 

Forel 2006 [13]

Low risk of bias

Low risk of bias

High risk of bias

Low risk of bias

Low risk of bias

Low risk. of bias

High

 

Computer-generated random number sequences

Centralized

Nurses aware of assignment; infusion covered by sheet

None

None

None

 

Papazian 2010 [14]

Low risk of bias

Low risk of bias

Low risk of bias

Low risk of bias

Low risk of bias

Low risk. of bias

Low

 

Computer-generated random number sequences

Centralized, using undisclosed block sizes

Blinding of patients, clinicians, evaluators, investigators, analysts

None

None

None

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