Physiological predictors of survival during high-frequency oscillatory ventilation inadults with acute respiratory distress syndrome

Table 1 Patient characteristics at study entry

Variable
Patient characteristics
Patients, number	102
Age, years	50.8 ± 15.9
Gender, % male	67.6
Actual body weight, Kg	75.7 ± 21.24
APACHEII prior HFOV	24.1 ±8.0
Murray Score	2.98 ± 0.7
Duration ARDS prior HFOV, hours median (IQR)	48 (24 to 120)
Duration CMV prior HFOV, hours median (IQR)	45 (9 to 138)
Gas exchange on CMV pre-HFOV
PaO₂, mmHg	74.2 ± 21
PaCO₂, mmHg	57.6 ± 18.7
PaO₂/FiO₂, mmHg	93.8 ± 38.3
SaO₂, %	88.6 ± 11.99
OI, cmH₂· mmHg^-1	27 ± 13.4
pH	7.26 ± 0.14
Respiratory variables on CMV pre-HFOV
PIP, cmH₂O	32.1 ± 5.67
PEEP, cmH₂O	12.4 ± 3.7
CDP, cmH₂O	21.6 ± 4.97
Compliance	26.4(19.9 to 36.3)
Minute ventilation, L^.min^-1	10.4 (8.5 to 12.6)
Respiratory rate	20.9 ± 5.1
Tidal volume on CMV, mL	551 (421.7 to 620)
Hemodynamics on CMV pre-HFOV
PAWP, cmH₂O	16.8 ± 7.1
Cardiac Output, L·min^-1	5.95 ± 1.7
Etiology of ARDS
Sepsis	69
Pulmonary infection	13
Trauma	3
Aspiration	2
Pancreatitis	2
Drug-induced	1
Other	12

Data are presented as absolute number, % or mean ± standard deviation (SD)unless otherwise indicated. CDP, continuous distending pressure; CMV, conventionalmechanical ventilation; CO, cardiac output; FiO_2, fraction of inspiredoxygen; HFOV, high-frequency oscillatory ventilation; PAWP, pulmonary artery wedgepressure; PEEP, positive end-expiratory pressure; PIP, peak inspiratory pressure;OI, oxygenation index (OI =(FiO₂•CDP•100)/PaO₂).

ISSN: 1364-8535