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Table 2 Demographic, diagnostic and treatment-related data in those with and without augmented renal clearance.

From: Augmented renal clearance in septic and traumatized patients with normal plasma creatinine concentrations: identifying at-risk patients

Variable

ARC (number = 41)

No ARC (number = 30)

P-value

Age, years, mean (SD)

34.1 (11.7)

53.7 (15.5)

<0.001

Male gender, number (%)

31 (75.6)

14 (46.7)

0.012

BSA, m2, mean (SD)

1.98 (0.25)

1.99 (0.28)

0.850

APACHE II score, mean (SD)

16.0 (6.33)

20.4 (7.49)

0.008

Modified SOFA score, median [IQR]

3 [2–4]

4 [3–6]

0.013

Use of vasopressors, number (%)

9 (22.0)

11 (36.7)

0.173

Mechanical ventilation, number (%)

39 (95.1)

27 (90.0)

0.644

24 hr Fluid balance, ml, mean (SD)

428 (2011)

967 (1684)

0.237

CI, L/min/m2, mean (SD)

4.47 (1.01)

3.80 (1.12)

0.013

CLCR, ml/min/1.73 m2, mean (SD)

170 (32.9)

86.8 (29.5)

<0.001

Category

Trauma, number (%)

Sepsis, number (%)

24 (58.5)

17 (41.5)

4 (13.3)

26 (86.7)

<0.001

<0.001

  1. APACHE II, Acute Physiology and Chronic Health Evaluation score; BSA, body surface area; CI, cardiac index; CLCR, creatinine clearance; SOFA, Sequential Organ Failure Assessment.
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