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Table 1 Laboratory, demographic and illness-severity data of all patients (n = 71).

From: Augmented renal clearance in septic and traumatized patients with normal plasma creatinine concentrations: identifying at-risk patients

Variable

All patients (number = 71)

Trauma (number = 28)

Sepsis (number = 43)

P-valuea

Age, years, mean (SD)

42.4 (16.6)

36.4 (13.9)

46.3 (17.1)

0.013

Male gender, number (%)

45 (63.4)

23 (82.1)

22 (51.2)

0.008

BSA, m2, mean (SD)

1.98 (0.26)

2.01 (0.25)

1.96 (0.27)

0.415

APACHE II score, mean (SD)

17.9 (7.15)

16.1 (7.68)

19.0 (6.62)

0.096

Modified SOFA score, median [IQR]

3 [2–5]

3.5 [2–5]

3 [2–5]

0.659

Use of Vasopressors, number (%)

20 (28.2)

11 (39.3)

9 (20.9)

0.093

Mechanical ventilation, number (%)

66 (93.0)

26 (92.9)

40 (93.0)

1.000

24hour Fluid balance, ml, mean (SD)

656 (1,886)

1,209 (1903)

295 (1,806)

0.045

Plasma CR, μmol/L, mean (SD)

66.1 (18.1)

62.7 (13.2)

68.4 (20.5)

0.157

CI, L/min/m2, mean (SD)

4.20 (1.10)

4.30 (0.86)

4.13 (1.23)

0.507

CLCR, ml/min/1.73 m2, mean (SD)

135 (51.8)

166 (42.5)

114 (47.2)

<0.001

Augmented renal clearance, n (%)

41 (57.7)

24 (85.7)

17 (39.5)

< 0.001

ICU length of stay, days, mean (SD)

16.0 (11.1)

13.3 (10.2)

17.8 (11.4)

0.090

ICU mortality, number (%)

3 (4.20)

1 (3.6)

2 (4.7)

1.000

Hospital mortality, number (%)

6 (8.50)

3 (10.7)

3 (7.0)

0.674

  1. aComparison between sub-groups. APAHCE II, Acute Physiology and Chronic Health Evaluation; BSA, body surface area; CI, cardiac index; CLCR, creatinine clearance; CR, creatinine concentration; SOFA, Sequential Organ Failure Assessment.