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Table 2 Correlation of NGAL and creatinine with various cytokines

From: Impact of sepsis-associated cytokine storm on plasma NGAL during acute kidney injury in a model of polymicrobial sepsis

 

NGAL

Crea

 

6 h sepsis

24 h sepsis

6 h sepsis

24 h sepsis

 

r

P -value

r

P -value

r

P -value

r

P -value

Crea resp. NGAL

0.48

<0.05

0.78

<0.001

0.48

<0.05

0.78

<0.001

IL6

-0.05

0.853

0.68

<0.01

0.38

0.095

0.73

<0.001

IL10

0.23

0.351

0.76

<0.001

0.38

0.103

0.77

<0.001

MCP1

0.36

0.127

0.74

<0.001

0.42

0.066

0.69

<0.01

IFNγ

0.25

0.293

0.22

0.383

0.37

0.114

0.03

0.909

TNFα

0.60

<0.01

0.70

<0.01

0.39

0.09

0.69

<0.01

  1. Spearman correlation analyses correlating plasma neutrophil gelatinase-associated lipocalin (NGAL) and creatinine (Crea) with various cytokines, all measured from samples of polymicrobial infected mice 6 h (n = 20) and 24 h (n = 18) post-sepsis induction. P-values are given. IFNγ, interferon-gamma; IL, interleukin; MCP1, monocyte chemotactic protein-1; TNF, tumour necrosis factor