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Table 2 Variables associated with plasma syndecan-1 by univariate and multivariate (backwards selection) linear regression analysis in 571 consecutive STEMI patients treated with primary PCI

From: Acute myocardial infarction is associated with endothelial glycocalyx and cell damage and a parallel increase in circulating catecholamines

  

Univariate

  

Multivariate

  
     

R2 = 0.05

  
  

β (95%CI)

t

P

β (95%CI)

t

P

Adrenaline

100 pg/ml

1.64 (0.58 to 2.71)

3

0.003

  

NS

Noradrenaline

100 pg/ml

1.20 (0.57 to 1.84)

4

<0.001

1.12 (0.46 to 1.78)

3

0.001

Male gender

yes

-24 (-41 to-8)

-3

0.004

  

NS

Diabetes

yes

29 (4 to 54)

2

0.024

31 (3 to 58)

2

0.032

eGFR

ml/min

-0.41 (-0.72 to-0.10)

-3

0.009

  

NS

Peak TnI

µg/L

0.04 (0 to 0.08)

2

0.051

  

NS

Shock prior to pPCI

yes

43 (17 to 69)

3

0.002

35 (8 to 61)

3

0.010

  1. Regression coefficients (β) with 95% confidence intervals (95%CI), t-and P-values and R2 displayed for the multivariate models. P-values are shown in bold for variables with P <0.05. Predicted change in syndecan-1 (pg/ml) associated with one unit increase in adrenaline, noradrenaline, eGFR and peak TnI, being male or having diabetes or shock prior to pPCI. eGFR, estimated glomerular filtration rate; pPCI, percutaneous primary coronary intervention; STEMI, ST elevation myocardial infarction; TnI, troponin I.
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