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Table 1 Characteristics of 15 observational studies including data on use of mild therapeutic hypothermia in patients with non-ventricular fibrillation/ventricular tachycardia (VF/VT) cardiac arrest

From: Therapeutic hypothermia: is it effective for non-VF/VT cardiac arrest?

   

Non-VF/VT

     

Author [Reference]

Arrest location

Patients

Total

Cooled

Initiation of hypothermia

Cooling method

Control group

Definition of poor outcome

Length of follow-up

Holzer 2006 [27]

Mixed (OHCA 67%)

1,038

534

28

In-hospital

Internal

Concurrent

CPC 3-5

30 days

Oddo 2006 [21]

OHCA

109

23

12

In-hospital

External

Historical

CPC 3-5

Discharge

Heer 2007 [26]

Mixed

76

18

10

In-hospital

Internal

Historical

NA

Discharge

Sunde 2007 [29]

OHCA

119

15

6

In-hospital

Mixed

Historical

CPC 3-5

Discharge

Arrich 2007 [23]

Mixed (OHCA 83%)

587

197

124

In-hospital

Mixed

Concurrent

CPC 3-5

Discharge

Rittenberger 2008 [38]

Mixed (OHCA 56%)

241

81

42

In-hospital

Mixed

Concurrent

Discharged to a nursing home

Discharge

Storm 2008 [28]

OHCA

126

49

18

In-hospital

Mixed

Historical

CPC 3-5

Discharge

Don 2009 [24]

OHCA

491

313

122

In-hospital

External

Historical

CPC 2-5

Discharge

Whitfield 2009 [30]

OHCA

123

28

15

Pre/In-hospital

Mixed

Historical

Discharged to a nursing home

Discharge

Gaieski 2009 [39]

OHCA

38

18

9

In-hospital

Mixed

Historical

CPC 3-5

Discharge

Bro-Jeppesen 2009 [25]

OHCA

156

48

27

Pre/In-hospital

Mixed

Historical

CPC 3-5

6 months

Derwall 2009 [37]

OHCA

68

28

13

In-hospital

Mixed

Concurrent

CPC 3-5

14 days

Dumas 2011 [33]

OHCA

1,145

437

261

In-hospital

External

Historical

CPC 3-5

Discharge

Storm 2012 [34]

Mixed (OHCA 73%)

387

175

87

In-hospital

Mixed

Historical

CPC 1-2

90 days

Lundbye 2012 [35]

Mixed (OHCA 52%)

100

100

52

In-hospital

Internal

Historical

CPC 3-5

Discharge

  1. OHCA: out-of-hospital cardiac arrest; CPC: Cerebral Performance Category.