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Table 2 Mild therapeutic hypothermia timing and temperature data

From: Automated peritoneal lavage: an extremely rapid and safe way to induce hypothermia in post-resuscitation patients

 

Control group

PL group

P-value

First temperature measured (°C)

35.0 (34.0 to 35.6)

35.0 (34.9 to 35.7)

0.14

Induction:

   

Start time (min)

74 (52 to 130)

169 (137 to 187)*

0.0001

Time to target temperature of 32.5°C (min)

150 (112 to 240)

30 (19 to 60)*

<0.0001

Cooling rate (°C/h)

0.9 (0.5 to 1.3)

4.1 (2.2 to 8.2)*

0.01

Maintenance:

   

Mean temperature (°C)

32.4 (32.1 to 32.8)

32.4 (32.4 to 32.5)

0.28

Lowest temperature (°C)

31.2 (31.0 to 31.7)

32.2 (32.2 to 32.3)*

<0.0001

Temperature <31°C, n (%)

23 (23)

0 (0)

0.066

Temperature variability (°C)

0.45 (0.38 to 0.70)

2.20 (1.70 to 3.05)*

<0.0001

Re-warming:

   

Duration to reach 36.5°C (h)

15.7 (11.0 to 23.0)

12.8 (10.0 to 14.8)*

0.005

  1. Continuous variables are median (interquartile range) and categorical variables are counts (percentages). PL, peritoneal lavage. *P ≤0.05 Lavage versus Control group.
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Critical Care

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