Table 2 Univariable analysis of admission and pretransplant factors for survivors versus nonsurvivors at 90 days in 198 transplanted critically ill cirrhosis patients (five sites)

Age

51 (11)

56 (8)

0.007

Age >60

30 (18%)

11 (34%)

0.037

Female

58/165 (35%)

9/32 (28%)

0.4

HCV

54/166 (33%)

8/32 (25%)

0.4

Biochemistry (admission)

Hemoglobin (g/L)

85 (24)

86 (21)

0.9

WBC (×10⁹/L)

9.2 (5.2-14.8)

8.0 (5.5-11.8)

0.4

Platelets (×10⁹/L)

62 (41-94)

71 (49-109)

0.14

INR

2.1 (1.7-2.7)

2.4 (1.8-3.0)

0.3

Bilirubin (μM)

272 (101-589)

269 (74-540)

0.4

Lactate (mM)

2.8 (1.7-4.6)

1.5 (1.1-4.6)

0.23

Sodium (mM)

136 (131-142)

136 (131-141)

0.7

Creatinine (μM)

195 (97-303)

225 (141-336)

0.17

Physiology (admission)

GCS

10 (4.5)

11 (4.5)

0.6

PO₂/FiO₂ ratio (mm Hg)

229 (102)

217 (132)

0.5

Mechanical ventilation

68/121 (56%)

8/13 (62%)

0.7

Vasoactive drugs

75/157 (48%)

9/29 (31%)

0.10

Renal replacement therapy

43/158 (27%)

6/29 (21%)

0.5

Child-Turcotte-Pugh score

Listing

12.5 (1.4)

12.9 (1.4)

0.5

MELD

Listing

24 (16-36)

27 (17-27)

0.85

Admission

34 (26-39)

34 (25-40)

0.6

Day of transplant

35 (26-40)

34 (28-40)

0.9

SOFA

Admission

13 (4)

12 (5)

0.11

48 hours

14 (5)

11 (4)

0.023

Day of transplant

14 (4)

11 (4)

0.15

ICU Length of stay

Before transplant

5 (3-10)

6 (2-14)

0.6

After transplant

9 (5-20)

8 (2-14)

0.05

Donor score (out of 4)

1 (1-2)

1 (1-2)

0.6

Partial graft

2/160 (1%)

0/30 (0)

0.5

Cold ischemia time >8 hours

88/157 (56%)

14/26 (54%)

0.8

Donor cerebrovascular accident

85/163 (52%)

20/30 (67%)

0.14

Donor age >60

29/162 (18%)

6/31 (19%)

0.8