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Figure 2 | Critical Care

Figure 2

From: Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury

Figure 2

Area under the receiver-operating characteristics curve (AUC) for novel urinary biomarkers and existing biomarkers of acute kidney injury for the primary Sapphire study endpoint (KDIGO stage 2 or 3 within 12 hours of sample collection). Samples were collected within 18 hours of enrollment. The AUC for urinary [TIMP-2]·[IGFBP7] is larger than for the existing biomarkers (P value <0.002). IGFBP7, insulin-like growth factor-binding protein 7; IL-18, interleukin-18; KIM-1, kidney injury marker-1; L-FABP, liver fatty acid-binding protein; NGAL, neutrophil gelatinase-associated lipocalin; pi-GST, pi-Glutathione S-transferase; TIMP-2, tissue inhibitor of metalloproteinases-2.

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