| |
Group
|
Pre-arrest
|
Post-resuscitation phase
|
Friedmann
|
|---|
| | | |
5 min
|
30 min
|
90 min
|
240 min
| |
|---|
|
pH hep ven
|
TELM
|
7.42 ± 0.01
|
7.21 ± 0.02*
|
7.29 ± 0.02
|
7.40 ± 0.01
|
7.44 ± 0.01
|
P < 0.0001
|
| |
Control
|
7.42 ± 0.01
|
7.24 ± 0.01*
|
7.31 ± 0.01
|
7.39 ± 0.01
|
7.43 ± 0.01
|
P < 0.001
|
|
PHVO2
|
TELM
|
37.9 ± 1.6
|
29.4 ± 3.2
|
36.3 ± 1.8
|
34.4 ± 3.8
|
33.4 ± 1.7
|
ns
|
|
(mmHg)
|
Control
|
34.7 ± 2.8
|
28.2 ± 3.3
|
31.7 ± 2.3
|
31.2 ± 2.0
|
29.1 ± 2.9
|
ns
|
|
PHVCO2
|
TELM
|
45.1 ± 1.1
|
57.7 ± 1.7*
|
52.1 ± 2.4
|
45.7 ± 1.1
|
45.9 ± 0.8
|
P < 0.0001
|
|
(mmHg)
|
Control
|
46.3 ± 1.5
|
58.9 ± 1.6*
|
54.0 ± 1.6
|
47.2 ± 0.8
|
45.8 ± 0.9
|
P < 0.001
|
|
BE
|
TELM
|
4.5 ± 0.5
|
-5.3 ± 1.0*
|
-1.8 ± 1.1
|
2.9 ± 1.3
|
6.1 ± 0.6
|
P < 0.0001
|
| |
Control
|
4.9 ± 0.4
|
-3.1 ± 0.4*
|
+0.1 ± 0.9
|
4.0 ± 1.4
|
5.7 ± 1.0
|
P < 0.001
|
- pH hep ven = hepatic venous pH; PHVO2 = hepatic venous partial pressure of oxygen; PHVCO2 = hepatic venous partial pressure of carbon dioxide; BE = base excess; TELM = angiotensin II antagonist telmisartan; ns = not significant. *P < 0.05 vs pre-arrest values by Wilcoxon matched pairs test.
