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Table 1 Hemodynamic variables, and myocardial and cerebral blood flow (mean ± SEM) pre-arrest, and during the post-resuscitation phase before and after drug administration

From: Effects of an angiotensin II antagonist on organ perfusion during the post-resuscitation phase in pigs

Variable Group Pre-arrest Post-resuscitation phase Friedmann
    5 min 30 min 90 min 240 min  
MAP TELM 114 ± 4 91 ± 7* 84 ± 3 91 ± 3     90 ± 2* P < 0.01
   (mmHg) Control   122 ± 11   93 ± 12* 91 ± 4 93 ± 4     92 ± 4* P < 0.05
CI TELM 115 ± 6 66 ± 7* 77 ± 7 98 ± 7 108 ± 5 P < 0.001
   (ml/min/kg) Control 129 ± 9 72 ± 7* 77 ± 4 114 ± 14   102 ± 5* P < 0.001
LVMBF TELM     1.9 ± 0.2 2.6 ± 0.4   1.3 ± 0.1   2.1 ± 0.4     2.3 ± 0.5 P < 0.05
   (ml/min/g) Control     2.1 ± 0.3 2.3 ± 0.3   1.4 ± 0.1   2.4 ± 0.3     2.6 ± 0.5 ns
Cortex TELM     0.36 ± 0.02   2.10 ± 0.36*   0.29 ± 0.02   0.32 ± 0.03       0.57 ± 0.14* P < 0.0001
   (ml/min/g) Control     0.38 ± 0.03   2.27 ± 0.31*   0.36 ± 0.02   0.44 ± 0.07       0.57 ± 0.05* P < 0.001
  1. CI = cardiac index; LVMBF = left ventricular myocardial blood flow; MAP = mean arterial pressure; ns = not significant; TELM = angiotensin II antagonist telmisartan. *P < 0.05 vs pre-arrest values by Wilcoxon matched pairs test.