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Table 4 Health-related quality of life in surviving patients without acute kidney injury and comparison with general population

From: The effect of acute kidney injury on long-term health-related quality of life: a prospective follow-up study

 

Pre-ICU, all patients

Pre-ICU, survivors (6 months)

ICU discharge

Hospital discharge

3 months after ICU discharge

6 months

after ICU

discharge

General population

(61- to 70-year-old age group)

Differences between pre-ICU survivors (n= 325) and pre-ICU non-survivors

(n= 168)a

Differences between pre-ICU survivors and general populationb

Differences between pre-ICU (n= 325) and 6 months after ICU discharge (n= 325)c

Differences between 6 months after ICU discharge and general populationb

Number

577

325

448

367

338

325

 

P value

Effect

sizes

P value

Effect

sizes

Wilks's lambda

Effect

sizes

P value

Effect

sizes

PCS

41.5 ± 13.6

44.0 ± 12.9

26.6 ± 6.5

32.5 ± 9.2

36.8 ± 10.5

39.1 ± 11.1

-

< 0.001d

0.57

-

-

< 0.001d

0.38

-

-

MCS

48.5 ± 10.3

50.1 ± 9.9

46.1 ± 9.3

47.9 ± 9.5

49.7 ± 10.9

50.7 ± 10.9

-

< 0.001d

0.35

-

-

0.241

0.06

-

-

PF

59.6 ± 34.6

66.6 ± 33.2

6.4 ± 12.9

30.8 ± 26.4

49.0 ± 32.4

54.3 ± 31.8

71.7 ± 25.6

< 0.001d

0.59

0.006

0.20

< 0.001d

0.37

< 0.001d

0.68

RP

52.5 ± 47.4

60.9 ± 46.7

14.4 ± 32.5

19.6 ± 35.7

28.9 ± 40.5

39.7 ± 45.6

67.3 ± 40.9

< 0.001d

0.54

0.014

0.16

< 0.001d

0.45

< 0.001d

0.67

BP

79.0 ± 26.9

80.2 ± 27.3

75.1 ± 25.0

82.1 ± 22.8

80.7 ± 24.0

84.0 ± 22.2

70.5 ± 24.6

0.238

0.14

< 0.001d

0.39

0.033d

0.14

< 0.001d

0.55

GH

50.9 ± 30.3

57.9 ± 28.9

31.1 ± 19.6

38.8 ± 27.4

44.7 ± 26.4

46.8 ± 24.9

61.7 ± 20.2

< 0.001d

0.57

0.019

0.19

< 0.001d

0.38

< 0.001d

0.74

VT

53.6 ± 24.1

58.9 ± 24.2

32.7 ± 15.9

44.9 ± 18.2

55.9 ± 22.8

58.9 ± 21.7

67.7 ± 19.6

< 0.001d

0.59

< 0.001d

0.45

0.610

0.10

< 0.001d

0.36

SF

71.8 ± 24.7

77.5 ± 24.6

52.1 ± 22.5

60.4 ± 24.8

69.1 ± 27.8

72.5 ± 24.8

82.0 ± 24.6

< 0.001d

0.56

0.001d

0.18

0.011d

0.20

< 0.001d

0.39

RE

74.8 ± 40.9

79.3 ± 39.0

60.9 ± 44.3

68.2 ± 45.6

70.0 ± 43.2

75.9 ± 40.9

81.1 ± 35.0

0.010d

0.29

0.412

0.05

0.383

0.08

0.027

0.15

MH

67.5 ± 16.7

70.9 ± 15.9

56.9 ± 11.5

63.1 ± 13.0

67.6 ± 16.1

69.2 ± 21.5

76.9 ± 17.9

< 0.001d

0.50

< 0.001d

0.34

0.461

0.08

< 0.001d

0.43

  1. Effect sizes of at least 0.20, at least 0.50, and greater than 0.80 correspond to small, medium, and large, respectively. Values are presented as mean ± standard deviation (SD). aUnivariate analysis of variance with Bonferroni correction P < 0.05 significant. bOne-sample t test. cGeneral linear model repeated measures with Bonferroni correction P < 0.05 significant. dP value significant after Bonferroni correction (P 0.05/10 = P = 0.005 = significant). SF-36 (Medical Outcomes Study 36-item Short-Form) dimension scores range from 0 to 100. Physical component score (PCS) and mental component score (MCS) are converted to mean 50 (SD 10). BP, bodily pain; GH, general health; ICU, intensive care unit; MH, mental health; PF, physical functioning; RE, role limitation due to emotional problems; RP, role limitation due to physical problems; SF, social functioning; VT, vitality.
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