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Table 4 Sensitivity analysis considering presence of AKI according to RIFLE classification.

From: Fluid balance and urine volume are independent predictors of mortality in acute kidney injury

 

Unadjusted

Adjusted

 

HR (95% CI)

P

HR (95% CI)

P

Mean fluid balance/24hours (L)

1.74 (1.56 to 1.95)

<0.001

1.51 (1.31 to 1.74)

<0.001

Mean urine volume/24hours (L)

0.39 (0.32 to 0.48)

<0.001

0.48 (0.38 to 0.62)

<0.001

Diuretic use

0.34 (0.22 to 0.52)

<0.001

0.31 (0.19 to 0.51)

<0.001

Diabetes

1.36 (0.88 to 2.10)

0.17

1.75 (1.08 to 2.85)

0.023

  1. Variables considered for the model included age, gender, co-morbid diseases (diabetes, hypertension and cardiovascular disease), non-renal SOFA, sepsis, mean fluid balance, mean urine volume and diuretic use. Only significant variables are shown in the table. AKI, acute kidney injury; HR, hazard ratio; RIFLE, Risk of renal dysfunction, Injury to the kidney, Failure of kidney function, Loss of kidney function and End-stage kidney disease.