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Table 4 Non-treated patients in the intervention group compared with treated and control group

From: Haloperidol prophylaxis in critically ill patients with a high risk for delirium

 

Control

group

(N= 299)

Intervention group

non-treated

(N= 59)

Intervention group

treated

(N= 177)

PRE-DELIRIC score (mean ± sd)

73 ± 22

77 ± 17

75 ± 19

Other risk

   

   - Alcohol abuse

41 (14%)

4 (7%)

20 (11%)

   - Dementia

5 (2%)

0

2 (1%)

Age (mean ±)

64 ± 14

62 ± 15

63 ± 14

Urgent admission (%)

261 (87%)

52 (88%)

152 (86%)

APACHE-II score

20 ± 7

20 ± 6

19 ± 6

Sepsis (%)

64 (21%)b

16 (28%)a

53 (30%)a

Gender (M/%)

181 (61%)

35 (59%)

115 (65%)

Admission specialism (N/%):

   

   - Surgical

75 (25%)

11 (19%)

33 (19%)

   - Medical

143 (48%)

30 (51%)

106 (60%)

   - Trauma

32 (11%)

5 (9%)

18 (10%)

   - Neurology/neurosurgical

49 (16%)

13 (22%)c

20 (11%)

Delirium incidence

225 (75%)b

53 (90%)a-b

115 (65%)

28 days delirium free without coma

13 (3 to 27)b

14 (1 to 22)b

20 (8 to 27)

28-day mortality

36 (12%)b

7 (12%)

13 (7%)

Re-intubation (%)

25 (8%)

8 (14%)

15 (9%)

Duration mechanical ventilation in hrs.

118 (39 to 250)

103 (54 to 251)

90 (36 to 229)

Unplanned removal tubes/lines (%)

58 (19%)b

13 (22%)b

21 (12%)

Re-admission

55 (18%)b

13 (22%)b

20 (11%)

LOS-ICU

7 (3 to 13)

7 (4 to 14)

6 (3 to 12)

LOS-in hospital

21 (12 to 41)

27 (13 to 48)b

20 (11 to 31)

  1. Data are presented as median, interquartile range (IQR), unless mentioned otherwise. a Statistically significantly different (P <0.05) compared with control group. b Statistically significantly different (P <0.05) compared with treated intervention group. c Borderline significant difference between non-treated and treated intervention group (P = 0.057).