Table 3 Differences between control group and complete intervention group divided in three delirium risk groups
From: Haloperidol prophylaxis in critically ill patients with a high risk for delirium
Predicted chance <71% | Control group (N= 110) | Intervention group (N= 69) | Differences (P-value) |
|---|---|---|---|
Predicted chance | 50 ± 19 | 55 ± 16 | 0.08 |
Age | 63 ± 13 | 63 ± 14 | 0.88 |
APACHE-II score | 17 ± 5 | 16 ± 5 | 0.12 |
Sepsis (%) | 11 (10%) | 18 (26%) | 0.005 |
Observed delirium incidence | 55 (50%) | 30 (44%) | 0.27 |
28 days delirium free without coma | 26 (10 to 28) | 26 (13 to 28) | 0.17 |
28-day mortality | 13 (12%) | 6 (9%) | 0.34* |
Re-intubation (%) | 5 (5%) | 6 (9%) | 0.25 |
Duration mechanical ventilation in hrs. | 42 (14 to 150) | 63 (15 to 168) | 0.43 |
Unplanned removal tubes/lines (%) | 14 (13%) | 7 (10%) | 0.41 |
   - Tube | 1 (1%) | 1 (2%) |  |
   - Gastric tube | 2 (2%) | 4 (6%) |  |
   - CVC/arterial line | 11(10%) | 1 (2%) |  |
   - Other | 0 (0%) | 1 (<1%) |  |
Re-admission | 18 (16%) | 4 (6%) | 0.03 |
LOS-ICU | 3 (2 to 8) | 4 (2 to 8) | 0.32 |
LOS-in hospital | 17 (9 to 31) | 16 (8 to 27) | 0.48 |
Predicted chance 71 to 89% | ( N = 111) | ( N = 60) | Differences |
Predicted chance | 81 ± 5 | 80 ± 5 | 0.66 |
Age | 64 ± 14 | 61 ± 15 | 0.14 |
APACHE-II score | 20 ± 6 | 20 ± 7 | 0.94 |
Sepsis (%) | 31 (28%) | 24 (40%) | 0.08 |
Observed delirium incidence | 94 (85%) | 44 (73%) | 0.06 |
28 days delirium free without coma | 11 (3 to 22) | 20 (7 to 27) | 0.02 |
28-day mortality | 13 (12%) | 5 (8%) | 0.93 |
Re-intubation (%) | 11 (11%) | 6 (10%) | 0.56 |
Duration mechanical ventilation in hrs. | 124 (55 to 278) | 133 (50 to 281) | 0.76 |
Unplanned removal tubes/lines (%) | 22 (20%) | 8 (13%) | 0.20 |
   - Tube | 4 (4%) | 2 (3%) |  |
   - Gastric tube | 12 (11%) | 6 (10%) |  |
   - CVC/arterial line | 6 (5%) | 0 (0%) |  |
Re-admission | 27 (24%) | 12 (20%) | 0.33 |
LOS-ICU | 8 (3 to 15) | 8 (4 to 17) | 0.57 |
LOS-in hospital | 23 (13 to 43) | 26 (16 to 41) | 0.99 |
Predicted chance >89% | ( N = 78) | ( N = 48) | Differences |
Predicted chance | 95 ± 3 | 95 ± 3 | 0.95 |
Age | 62 ± 16 | 65 ± 12 | 0.34 |
APACHE-II score | 24 ± 8 | 21 ± 6 | 0.05 |
Sepsis (%) | 22 (28%) | 11(23%) | 0.33 |
Observed delirium incidence | 76 (97%) | 41 (85%) | 0.06 |
28 days delirium free without coma | 4 (0 to 14) | 13 (6 to 21) | 0.002 |
28-day mortality | 10 (13%) | 2 (4%) | 0.07 †|
Re-intubation (%) | 9 (12%) | 3 (6%) | 0.25 |
Duration mechanical ventilation in hrs. | 185 (112 to 353) | 94 (62 to 266) | 0.02 |
Unplanned removal tubes/lines (%) | 22 (28%) | 6 (13%) | 0.04 |
   - Tube | 3 (4%) | 1 (2%) |  |
   - Gastric tube | 12 (15%) | 3 (6%) |  |
   - CVC/arterial line | 7 (9%) | 0 (0%) |  |
   - Other | 0 (0%) | 2 (4%) |  |
Re-admission | 10 (13%) | 4 (8%) | 0.32 |
LOS-ICU | 11 (7 to 18) | 6 (4 to 15) | 0.03 |
LOS-in hospital | 30 (14 to 56) | 20 (15 to 31) | 0.07 |