Skip to main content

Table 6 Frequency of patients with outlying values of laboratory safety assays and all-cause organ and system impairment.

From: The efficacy of thymosin alpha 1 for severe sepsis (ETASS): a multicenter, single-blind, randomized and controlled trial

 

Control group

No. (%) (n= 180)

Tα1 group

No. (%) (n= 181)

P value

Laboratory safety assays

   ALT (U/L)

43 (23.9)

38 (21.0)

0.51

   AST (U/L)

44 (24.4)

43 (23.8)

0.88

   Hypoglycemia

9 (5.0)

8 (4.4)

0.79

   Hemoglobin (g/L)

23 (12.8)

27 (14.9)

0.56

   Platelets (103/mm3)

77 (42.8)

67 (37.0)

0.26

   Creatinine (mmol/L)

12 (6.7)

18 (9.9)

0.26

SOFA component scores*

   Respiratory system

27 (15.0)

24 (13.3)

0.64

   Coagulation system

52 (28.9)

48 (26.5)

0.62

   Cardiovascular system

21 (11.7)

28 (15.5)

0.29

   Hepatic system

25 (13.9)

21 (11.6)

0.51

   Nervous system

22 (12.2)

14 (7.7)

0.15

   Renal system

19 (10.6)

26 (14.4)

0.27

  1. *Organ and system impairment based on the deterioration of SOFA component scores during the treatment. ALT, alanine aminotransferase; AST, aspartate aminotransferase; SOFA, Sequential Organ Failure Assessment; Tα1, thymosin alpha 1.