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Figure 4 | Critical Care

Figure 4

From: Protease-activated receptor-1 impairs host defense in murine pneumococcal pneumonia: a controlled laboratory study

Figure 4

Reduced pulmonary neutrophil influx in protease-activated receptor-1 knockout mice in later stage of murine pneumococcal pneumonia. Representative slides of lung Ly-6G staining (brown) 24 and 48 hours after induction of pneumococcal pneumonia in (A) wild-type and (B) protease-activated receptor-1 knockout mice (200 times original magnification). (C) Quantitation of pulmonary Ly-6G 48 hours after induction of pneumococcal pneumonia in wild-type (open bars) and protease-activated receptor-1 knockout mice (grey bars). Data are expressed as box-and-whisker diagrams depicting the smallest observation, lower quartile, median, upper quartile and largest observation (eight mice per group). * indicates statistical significance as compared to wild-type (P <0.05, Mann-Whitney U test).

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ISSN: 1364-8535