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Table 2 Univariate analysis of hospitalization characteristics, chronic conditions, and mortality by body mass index category.

From: Lower short- and long-term mortality associated with overweight and obesity in a large cohort study of adult intensive care unit patients

 

Total

Underweight

(BMI < 18.5 kg/m2)

Normal weight

(BMI 18.5 to < 25 kg/m2)

Overweight

(BMI 25 to < 30 kg/m2)

Obese

(BMI ≥ 30 kg/m2)

P valuea

Admission type, n (%)

     

< 0.001

   Elective

2,656 (15.8)

60 (7.6)b

776 (14.2)

888 (16.8)b

932 (17.6)b

< 0.001

   Emergency

13,342 (79.4)

693 (88.2)b

4,449 (81.4)

4,137 (78.4)b

4,063 (76.9)b

< 0.001

   Urgent

814 (4.8)

33 (4.2)

238 (4.4)

251 (4.8)

292 (5.5)b

0.004

ICU First Service, n (%)

     

< 0.001

   CCU

2,944 (17.5)

95 (12.1)b

889 (16.3)

1,016 (19.3)b

944 (17.9)b

< 0.001

   CSRU

3,885 (23.1)

78 (9.9)b

1,123 (20.6)

1,395 (26.4)b

1,289 (24.4)b

< 0.001

   MICU

5,657 (33.7)

399 (50.8)b

1,907 (34.9)

1,566 (29.7)b

1,785 (33.8)

< 0.001

   SICU

4,326 (25.7)

214 (27.2)

1,544 (28.3)

1,299 (24.6)b

1,269 (24.0)b

< 0.001

SAPS,c mean (SD)

12.1 (5.3)

12.3 (5.3)

12.2 (5.4)

12.0 (5.3)b

12.0 (5.3)b

0.87

Smoker, n (%)d

5,647 (33.9)

256 (32.5)

1,752 (32.1)

1,831 (34.7)b

1,808 (34.2)

0.25

Obesity-related conditions

      

   Diabetes

4,334 (25.8)

117 (14.9)b

1,062 (19.4)

1,300 (24.6)b

1,855 (35.1)b

< 0.001

   Coronary artery disease

6,612 (39.3)

182 (23.2)b

1,962 (35.9)

2,330 (44.2)b

2,138 (40.4)b

< 0.001

   Stroke

2,014 (12.0)

92 (11.7)

715 (13.1)

643 (12.2)

564 (10.7)b

< 0.001

   Hypertension

8,647 (51.4)

311 (39.6)b

2,516 (46.1)

2,827 (53.6)b

2,993 (56.6)b

< 0.001

   Other CVD

10,066 (59.9)

433 (55.1)b

3,257 (59.6)

3,208 (60.8)

3,168 (59.9)

0.16

   Obesity-related cancere

384 (2.3)

20 (2.5)

130 (2.4)

115 (2.2)

119 (2.3)

0.54

   Kidney disease

4,118 (24.5)

200 (25.5)

1,271 (23.3)

1,234 (23.4)

1,413 (26.7)b

< 0.001

   Osteoarthritis

280 (1.7)

7 (0.9)

53 (1.0)

92 (1.7)b

128 (2.4)b

< 0.001

Other relevant diagnoses, n (%)

      

   Pulmonary embolism

328 (2.0)

16 (2.0)

79 (1.5)

101 (1.9)

132 (2.5)b

< 0.001

   Sepsis

1,194 (7.1)

73 (9.3)b

369 (6.8)

353 (6.7)

399 (7.6)

0.60

   Wound/skin infection

733 (4.4)

26 (3.3)

186 (3.4)

197 (3.7)

324 (6.1)b

< 0.001

ICU interventions, n (%)

      

   Dialysis

1,322 (7.9)

56 (7.1)

417 (7.6)

373 (7.1)

476 (9.0)b

0.007

   Ventilation

11,201 (66.6)

469 (59.7)b

3,574 (65.4)

3,551 (67.3)b

3,607 (68.2)b

< 0.001

   Insulin

6,533 (38.9)

194 (24.7)b

1,912 (35.0)

2,198 (41.7)b

2,229 (42.2)b

< 0.001

   Transfusion

6,157 (36.6)

276 (35.1)

2,035 (37.3)

1,987 (37.7)

1,859 (35.2)b

0.09

   TPN

1,059 (6.3)

59 (7.5)

346 (6.3)

320 (6.1)

334 (6.3)

0.56

Length of stay

      

   ICU LOS, median (Q1-Q3)

2.3 (1.2-4.8)

2.3 (1.1-4.4)

2.3 (1.2-4.8)

2.3 (1.2-4.7)

2.3 (1.2-4.9)

0.11

   Hospital LOS, median (Q1-Q3)

8 (4-13)

8 (4-14)

8 (5-13)

7 (4-13)

8 (5-14)

0.97

Mortalityf

      

   Hospital mortality, n (%)

2,047 (12.2)

148 (18.8)b

799 (14.6)

551 (10.4)b

549 (10.4)b

< 0.001

   Mortality 30 days, n (%)

2,339 (13.9)

185 (23.5)b

910 (16.7)

644 (12.2)b

600 (11.4)b

< 0.001

   Mortality one year, n (%)

4,392 (26.1)

363 (46.2)b

1,720 (31.5)

1,203 (22.8)b

1,106 (20.9)b

< 0.001

  1. aP value for association or trend across BMI categories. bP < 0.05 compared with normal weight. cSAPS was calculated without the age component because age was an independent variable in the analysis. dIf smoker status was unknown, they were treated as "no." However, trends were the same when looking at those with data (known status). eObesity-related cancers: breast, colon, uterine, esophageal, pancreatic, ovarian, and kidney. fThe mortality numbers are cumulative (that is, the 1-year mortality group includes the 30-day mortality group. Likewise, the 30-day mortality group includes most of the patients who died in the hospital; however, the few patients that died in the hospital after 30 days were not included in the 30-day mortality.
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Critical Care

ISSN: 1364-8535