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Table 1 Patient characteristics

From: The clinical usefulness of extravascular lung water and pulmonary vascular permeability index to diagnose and characterize pulmonary edema: a prospective multicenter study on the quantitative differential diagnostic definition for acute lung injury/acute respiratory distress syndrome

Variable All (n= 266) ALI/ARDS (n= 207) Cardiogenic edema (n= 26) Pleural effusion with atelectasis (n= 33)
Age (years) 67.3 ± 16.2 66.7 ± 16.8 70.0 ± 12.5 69.4 ± 14.3
Male 175 (65.3%) 134 (64.7%) 14 (53.8%) 27 (77.1%)
Height (cm) 159.8 ± 10.0 159.4 ± 10.0 157.8 ± 10.4 163.4 ± 9.3
Body weight (kg) 55.2 ± 10.6 54.8 ± 10.6 52.8 ± 11.1 59.2 ± 9.8
BSA (m2) 1.56 ± 0.20 1.55 ± 0.20 1.52 ± 0.21 1.64 ± 0.18
Body mass index 21.3 ± 1.8 21.3 ± 1.8 20.9 ± 1.9 22.0 ± 1.5
Heart rate (beats/minute) 102 ± 25 103 ± 22 95 ± 26 103 ± 37
MAP (mmHg) 77 ± 18 76 ± 17 80 ± 18 79 ± 20
Vasopressor 180 (70.7%) 148 (71.5%)* 10 (38.5%)## 22 (66.7%)
Sepsis 144 (54.1%) 128 (61.8%)*,# 4 (15.4%) 12 (36.3%)
APACHE II score (points) 22.7 ± 8.0 23.4 ± 8.1** 19.7 ± 6.5 20.7 ± 7.7
SOFA score (points) 10.4 ± 3.7 10.7 ± 3.6* 8.1 ± 3.9 10.3 ± 3.5
   Respiratory 1.2 ± 1.2 1.2 ± 1.3 0.77 ± 1.1 1.5 ± 0.9
   Coagulation 0.9 ± 1.2 0.9 ± 1.1 1.0 ± 1.5 0.9 ± 1.1
   Liver 2.3 ± 1.7 2.5 ± 1.6* 1.3 ± 1.6## 2.4 ± 1.7
   Cardiovascular 0.7 ± 1.0 0.7 ± 1.0 0.4 ± 0.8 0.8 ± 1.0
   Central nervous system 3.0 ± 0.8 3.1 ± 0.8* 2.8 ± 0.7 2.7 ± 0.7
   Renal 2.3 ± 1.4 2.4 ± 1.4 2.0 ± 1.3 2.0 ± 1.5
PEEP (cmH2O) 8.6 ± 4.5 8.7 ± 4.7 7.9 ± 4.2 8.9 ± 3.5
Plateau pressure (cmH2O) 22.1 ± 5.7 22.3 ± 5.6 20.6 ± 6.9 21.5 ± 5.2
PaO2/FIO2 ratio (mmHg) 155.3 ± 70.7 150.5 ± 70.9 166.7 ± 69.8 176.2 ± 67.5
Lung Injury Score (points) 2.3 ± 0.6 2.3 ± 0.6# 2.3 ± 0.6 1.8 ± 0.7
Ejection fraction (%) 55.1 ± 13.1* 56.4 ± 12.1* 46.8 ± 13.0 55.0 ± 17.0
Stroke volume variation (%) 15 ± 7 16 ± 7* 11 ± 6## 16 ± 7
Cardiac index (l/m2/minute) 3.4 ± 1.2 3.5 ± 1.3 3.0 ± 1.0 3.4 ± 1.2
ITBV (ml/m2) 1040 ± 303 1021 ± 257* 1312 ± 527## 948 ± 215
EVLWI (ml/kg) 16.8 ± 7.1 18.5 ± 6.8*,# 14.4 ± 4.0# 8.3 ± 2.1
PVPI 2.9 ± 1.4 3.2 ± 1.4*,# 2.0 ± 0.8 1.6 ± 0.5
Maximal EVLWI (ml/kg) 19.2 ± 8.5 21.2 ± 8.1*,# 16.4 ± 7.5# 9.4 ± 2.1
Maximal PVPI 3.4 ± 1.6 3.7 ± 1.6*,# 2.2 ± 1.2 1.9 ± 0.6
VFD within 28 days (days) 11.3 ± 10.3 9.8 ± 9.9* 20.3 ± 8.0## 13.1 ± 10.7
28-day mortality 99 (37.2%) 84 (40.6%) 7 (26.9%) (24.2%)
  1. Data presented as mean ± standard deviation or n (%). Data on the day of enrollment were presented, except for maximal extravascular lung water index (EVLWI), and maximal pulmonary vascular permeability index (PVPI) during the 3-day study period. ALI/ARDS, acute lung injury/acute respiratory distress syndrome; APACHE, Acute Physiology and Chronic Health Evaluation; BSA, body surface area; ITBV, intrathoracic blood volume index; MAP, mean arterial pressure; PEEP, positive end-expiratory pressure; SOFA, Sequential Organ Failure Assessment; VFD, ventilator-free days. *P < 0.01 vs. cardiogenic edema, **P < 0.05 vs. cardiogenic edema, #P < 0.01 vs. pleural effusion with atelectasis, ##P < 0.05 vs. pleural effusion with atelectasis.