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Table 6 Association of in-hospital mortality and acute kidney injury and underlying chronic kidney disease

From: Severe hyperkalemia requiring hospitalization: predictors of mortality

   Univariate analysis Multiple logistic
regression analysisa
  Number OR (95% CI) P OR (95% CI) P
CKD- AKI+ 199 Reference   Reference  
CKD- AKI- 76 0.22 (0.12-0.40) < 0.001 0.65 (0.26-1.62) 0.357
CKD+ AKI- 165 0.13 (0.08-0.21) < 0.001 0.52 (0.25-1.12) 0.095
CKD+ AKI+ 483 0.21 (0.15-0.30) < 0.001 0.42 (0.23-0.74) 0.003
  1. aCovariables: gender, age, serum K+ level, the differences between the admission and highest serum K+ levels, diabetes mellitus, hypertension, malignancy, history of recurrence, angiotensin-converting enzyme inhibitor, angiotensin II receptor blocker, beta blocker, K+-sparing diuretics, non-steroidal anti-inflammatory drugs, infection, volume depletion, bleeding, poor compliance, transfusion, new-onset acute kidney injury (AKI), AKI on chronic kidney disease (CKD), multi-organ failure at the time of diagnosis, the type of admission, onset of hyperkalemia, symptoms pertinent to hyperkalemia, level of support I, and intensive care unit treatment. CI, confidence interval; OR, odds ratio.