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Table 2 Management and clinical outcomes of severe hyperkalemia

From: Severe hyperkalemia requiring hospitalization: predictors of mortality

Management

Number (percentage) unless indicated otherwise

Conservative management

   Drug cessation

219 (23.7)

   Calcium gluconate IV

536 (58.1)

   Dextrose fluid + insulin

486 (52.7)

   Sodium bicarbonate IV or PO

354 (38.4)

   Calcium polystyrene sulfonate enema

279 (30.2)

   Calcium polystyrene sulfonate PO

455 (49.3)

   Loop diuretics IV or PO

98 (10.6)

Renal replacement therapy

   Hemodialysis

176 (19.1)

   Continuous renal replacement therapy

71 (7.7)

Level of support I offered to patientsa

2.6 ± 1.8

Level of support II offered to patientsa

3.0 ± 1.9

Clinical outcomes

Number (percentage)

Intensive care unit (ICU) treatment

   No ICU care

601 (65.1)

   Need for ICU care

126 (13.7)

   During ICU care

196 (21.2)

   Reasons for ICU admission

 

Respiratory problem

146 (46.1)

Cardiac problem

26 (8.2)

Septic shock

32 (10.1)

Bleeding

17 (5.4)

Hemodynamic intensive monitoring

76 (24.0)

Others

20 (6.3)

Cardiopulmonary resuscitation (CPR)

 

   No CPR

631 (68.4)

   CPR for issues related to severe hyperkalemia

60 (7.5)

   CPR for other reasons

232 (25.1)

Improvement in severe hyperkalemia

715 (77.5)

In-hospital mortality (death)

283 (30.7)

   Reasons for in-hospital mortality

 

Respiratory problem

45 (15.9)

Cardiac problem

42 (14.8)

Septic shock

78 (27.6)

Progression of malignancy

20 (7.1)

Bleeding

35 (12.4)

Neurologic problem

20 (7.1)

Hepatic problem

23 (8.0)

Others

20 (7.1)

  1. aMean ± standard deviation. IV, intravenous; PO, by mouth (per os).