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Table 4 Comparison of main variables before intubation and cosyntropin test results between day-28 survivors and nonsurvivors

From: Effects of etomidate on complications related to intubation and on mortality in septic shock patients treated with hydrocortisone: a propensity score analysis

    

Multivariate analysis

 

Survivors ( n = 66)

Nonsurvivors ( n = 36)

P value

Hazard ratio (95% CI)

P value

SAPS II upon ICU admission

45 (37 to 55)

60 (47 to 71)

< 0.01

1.04 (1.01 to 1.06)

< 0.01

SOFA score upon ICU admission

8 (5 to 11)

11 (8 to 13)

0.08

1.01 (0.89 to 1.16)

0.85

Main variables obtained before intubation

     

   Vasopressor use

10 (15)

11 (31)

> 0.99

  

Drug used to facilitate intubation

     

   Etomidate

41 (62)

19 (53)

0.17

0.33 (0.12 to 0.90)

0.03

   Other

25 (38)

17 (47)

0.81

  

   Myorelaxants

62 (94)

35 (97)

0.46

  

Basal cortisol plasma level (μg/dl)

20 (14 to 40)

33 (19 to 49)

0.08

0.99 (0.96 to 1.03)

0.85

Cortisol plasma level after ACTH test (μg/dl)

31 (18 to 44)

35 (21 to 48)

0.54

  

Cosyntropin test responders

21/59 (36)

4/22 (19)

0.13

  
  1. Data presented as number (%) or median (quartiles). Multivariate analysis was performed using a Cox regression analysis for mortality. All variables with P < 0.20 in the univariate analysis were entered in the model. ACTH, Adrenocorticotropic hormone; CI, confidence interval; SAPS II, Simplified Acute Physiology Score II [35]; 95% CI: 95% confidence interval; SOFA, Sequential Organ Failure Assessment [36].