|  |  |  | Multivariate analysis | |
---|---|---|---|---|---|
 | Survivors ( n = 66) | Nonsurvivors ( n = 36) | P value | Hazard ratio (95% CI) | P value |
SAPS II upon ICU admission | 45 (37 to 55) | 60 (47 to 71) | < 0.01 | 1.04 (1.01 to 1.06) | < 0.01 |
SOFA score upon ICU admission | 8 (5 to 11) | 11 (8 to 13) | 0.08 | 1.01 (0.89 to 1.16) | 0.85 |
Main variables obtained before intubation | Â | Â | Â | Â | Â |
   Vasopressor use | 10 (15) | 11 (31) | > 0.99 |  |  |
Drug used to facilitate intubation | Â | Â | Â | Â | Â |
   Etomidate | 41 (62) | 19 (53) | 0.17 | 0.33 (0.12 to 0.90) | 0.03 |
   Other | 25 (38) | 17 (47) | 0.81 |  |  |
   Myorelaxants | 62 (94) | 35 (97) | 0.46 |  |  |
Basal cortisol plasma level (μg/dl) | 20 (14 to 40) | 33 (19 to 49) | 0.08 | 0.99 (0.96 to 1.03) | 0.85 |
Cortisol plasma level after ACTH test (μg/dl) | 31 (18 to 44) | 35 (21 to 48) | 0.54 |  |  |
Cosyntropin test responders | 21/59 (36) | 4/22 (19) | 0.13 | Â | Â |