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Table 1 Baseline characteristics of the 102 studied patients

From: Effects of etomidate on complications related to intubation and on mortality in septic shock patients treated with hydrocortisone: a propensity score analysis

Characteristic

All patients (n= 102)

Etomidate cohort (n= 60)

Non-etomidate cohort (n= 42)

P value

Age (years)

69 (58 to 75)

71 (62 to 72)

68 (56 to 73)

0.18

Male gender

72 (71)

44 (73)

28 (67)

0.002

Body mass index (kg/m2)

25 (23 to 30)

25 (23 to 29)

26 (24 to 32)

0.31

SAPS II upon ICU admission

48 (40 to 63)

52 (42 to 65)

46 (34 to 58)

0.049

SOFA score upon ICU admission

8 (6 to 12)

10 (7 to 13)

8 (6 to 11)

0.04

Previous disease

    

   Hypertension

43 (42)

26 (43)

17 (41)

0.77

   Coronary artery disease

22 (22)

14 (23)

8 (19)

0.04

   Congestive heart failure

29 (28)

17 (27)

12 (29)

0.98

   Neurological disease

20 (20)

11 (18)

9 (21)

0.70

   Chronic obstructive pulmonary disease

18 (18)

10 (17)

8 (19)

0.76

   Diabetes mellitus

20 (20)

10 (17)

10 (24)

0.37

   Cancer

41 (40)

26 (43)

15 (36)

0.44

   Liver cirrhosis

22 (21)

14 (23)

8 (19)

0.61

Admitting diagnosis group

    

   Medical

42 (41)

27 (45)

15 (36)

0.35

   Emergency surgery

45 (44)

23 (38)

22 (52)

0.16

   Elective surgery

15 (15)

10 (17)

5 (12)

0.55

Time from infection diagnostic to surgery (hours)

8 (4 to 24)

8 (5 to 24)

8 (4 to 24)

> 0.99

Source of sepsis

    

   Pulmonary

33 (32)

21 (35)

12 (29)

0.49

   Abdominal

54 (53)

25 (42)

29 (69)

0.02

   Other

15 (15)

14 (23)

1 (2)

0.03

Appropriateness of initial antibiotic therapy

68/89 (76)

39/52 (75)

29/37 (78)

0.71

Main variables obtained before intubation

    

   Systolic blood pressure < 90 mmHg

22(39)

15 (45)

7 (29)

0.31

   SpO2 below 80%

6 (10)

5 (15)

1 (4)

0.21

   Lactatemia (mmol/l)

2.5 (1.1 to 4.7)

2.5 (1.1 to 5.3)

2.3 (1.4 to 4.1)

0.80

   Vasopressors use

21 (21)

16 (27)

5 (12)

0.09

   Myorelaxant use to facilitate intubation

97 (98)

57 (95)

40 (98)

0.96

  1. Data presented as number (%) or median (quartiles). Appropriateness of initial antibiotic therapy was expressed as the number of appropriate first-line antibiotic therapies over the number of charts that were exploitable. SAPS II, Simplified Acute Physiology Score II [35]; SOFA, Sequential Organ Failure Assessment [36].