Skip to main content

Table 5 Univariate analysis of factors associated with in-hospital mortality

From: Antibiotic prescription patterns in the empiric therapy of severe sepsis: combination of antimicrobials with different mechanisms of action reduces mortality

 

Global

n= 1,372

Survivors

n= 846 (61.7%)

Nonsurvivors

n= 526 (38.3%)

P

General data

Sex (male)

837 (61.0%)

489 (57.8%)

348 (66.2%)

0.002

Age (years)

62.2 ± 16.2

59.80 ± 16.81

66.16 ± 14.39

<0.001

APACHE II

21.4 ± 7.5

19.20 ± 6.86

25.09 ± 7.17

<0.001

Lactate (mM)

35.6 ± 26.9

31.09 ± 22.54

43.09 ± 31.69

<0.001

Type of infection

Pneumonia

502 (36.6%)

289 (34.2%)

213 (40.5%)

 

Abdominal

390 (28.4%)

228 (27%)

162 (30.8%)

 

Urologic

181 (13.3%)

142 (16.8%)

40 (7.6%)

 

Meningitis

50 (3.6%)

40 (4.7%)

10 (1.9%)

<0.001

Skin and soft-tissue

54 (3.9%)

37 (4.4%)

17 (3.2%)

 

Catheter

24 (1.7%)

15 (1.8%)

9 (1.7%)

 

Others

138 (10.1%)

78 (9.2%)

60 (11.4%)

 

More than one focus

32 (2.3%)

17 (2%)

15 (2.9%)

 

Community acquired

1,022 (74.5%)

666 (78.7%)

356 (67.7%)

<0.001

DCCT

388 (28.3%)

256 (30.3%)

132 (25.1%)

0.042