Table 3 Distribution of baseline qualifying Gram-negative pathogens
| Â | Doripenem | Imipenem | Total |
|---|---|---|---|
| Â | ( N = 79) | ( N = 88) | ( N = 167) |
| Â | n (%) | n (%) | n (%) |
Specific Gram-negative Pathogens | 65 (82.3) | 62 (70.5) | 127 (76.0) |
   Pseudomonas aeruginosa | 17 (21.5) | 10 (11.4) | 27 (16.2) |
   Monomicrobial* | 8 ( 10.1) | 6 (6.8) | 14 (8.4) |
   Polymicrobial** | 9 (11.4) | 4 (4.5) | 13 (7.8) |
   Acinetobacter spp. | 15 (19.0) | 10 (11.4) | 25 (15.0) |
   Monomicrobial* | 3 (3.8) | 4 (4.5) | 7 (4.2) |
   Polymicrobial** | 12 (15.2) | 6 (6.8) | 18 (10.8) |
Enterobacteriaceae | 43 (54.4) | 49 (55.7) | 92 (55.1) |
   Monomicrobial* | 14 (17.7) | 14 (15.9) | 28 (16.8) |
Citrobacter koseri | 1 (1.3) | 0 | 1 (0.6) |
Enterobacter aerogenes | 0 | 1 (1.1) | 1 (0.6) |
Enterobacter cloacae | 4 (5.1) | 3 (3.4) | 7 (4.2) |
Escherichia coli | 1 (1.3) | 2 (2.3) | 3 (1.8) |
Klebsiella pneumoniae | 5 (6.3) | 4 (4.5) | 9 (5.4) |
Pantoea agglomerans | 1 (1.3) | 0 | 1 (0.6) |
Proteus mirabilis | 1 (1.3) | 2 (2.3) | 3 (1.8) |
Serratia marcescens | 1 (1.3) | 2 (2.3) | 3 (1.8) |
   Polymicrobial** | 29 (36.7) | 35 (39.8) | 64 (38.3) |
Citrobacter freundii | 0 | 3 (3.4) | 3 (1.8) |
Enterobacter aerogenes | 0 | 2 (2.3) | 2 (1.2) |
Enterobacter asburiae | 1 (1.3) | 0 | 1 (0.6) |
Enterobacter cloacae | 4 (5.1) | 2 (2.3) | 6 (3.6) |
Enterobacter spp. (Not Speciated) | 1 (1.3) | 0 | 1 (0.6) |
Escherichia coli | 5 (6.3) | 12 (13.6) | 17 (10.2) |
Klebsiella oxytoca | 1 (1.3) | 1 (1.1) | 2 (1.2) |
Klebsiella pneumoniae | 14 (17.7) | 16 (18.2) | 30 (18.0) |
Proteus mirabilis | 3 (3.8) | 3 (3.4) | 6 (3.6) |
Proteus vulgaris | 1 (1.3) | 1 (1.1) | 2 (1.2) |
Providencia spp. (Not Speciated) | 0 | 1 (1.1) | 1 (0.6) |
Serratia marcescens | 3 (3.8) | 3 (3.4) | 6 (3.6) |
Pneumonia with MRS | 7 (8.9) | 4 (4.5) | 11 (6.6) |
   Pseudomonas aeruginosa | 2 (2.5) | 1 (1.1) | 3 (1.8) |
   Polymicrobial** | 2 (2.5) | 1 (1.1) | 3 (1.8) |
Acinetobacter spp. | 2 (2.5) | 1 (1.1) | 3 (1.8) |
   Polymicrobial** | 2 (2.5) | 1 (1.1) | 3 (1.8) |
Enterobacteriaceae | 4 (5.1) | 2 (2.3) | 6 (3.6) |
   Polymicrobial** | 4 (5.1) | 2 (2.3) | 6 (3.6) |