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Table 1 Characteristics of included studies

From: Clinical review: Predictive value of neutrophil gelatinase-associated lipocalin for acute kidney injury in intensive care patients

Study Year Population size Patients NGAL sample Assay AKI definition
de Geus et al. [21] 2011 632 General ICU Plasma and urine FIA RIFLE (sCr)
Endre et al. [22, 23] 2011 528 General ICU Urine ELISA AKIN or RIFLE (sCr)
Doi et al. [24] 2011 339 General ICU Urine ELISA RIFLE (sCr)
Cruz et al. [25] 2010 301 General ICU Plasma FIA RIFLE (sCr + UO)
Constantin et al. [26] 2010 88 General ICU Plasma FIA RIFLE (sCr)
MÃ¥rtensson et al. [27] 2010 25 ICU patients with septic shock Plasma and urine RIA RIFLE and AKIN (sCr + UO)
Metzger et al. [28] 2010 20 General ICU Urine ELISA AKIN (sCr + UO)
Siew et al. [29] 2009 451 General ICU Urine ELISA AKIN (sCr)
Makris et al. [30] 2009 31 ICU patients with multiple trauma Urine ELISA RIFLE (sCr + UO)
Kokkoris et al.a [31] 2011 91 General ICU Plasma FIA RIFLE (sCr + UO)
Linko et al.b 2012 369 General ICU Plasma FIA -
  1. aStudy published as abstract only; author contacted to obtain extracted data; bstudy unpublished. AKI, acute kidney injury; AKIN, Acute Kidney Injury Network; ELISA, enzyme-linked immunosorbent assay; FIA, fluorescence immunoassay; RIA, radioimmunoassay; RIFLE, Risk, Injury, Failure, Loss, and End-stage kidney disease; sCr, serum creatinine; UO, urine output.