From: Outcome of ICU patients with Clostridium difficile infection
Characteristics | Tested patients (n= 512) | Patients with ICU-acquired CDI (n= 47) | Patients without ICU-acquired CDI (n= 5,213) |
---|---|---|---|
Age | 67 (56 to 76) | 63 (55 to 75) | 64 (51 to 76) |
Male | 315 (61.5) | 29 (61.7) | 3,172 (60.9) |
Category of admission | |||
Medicine | 384 (75) | 38 (80.9) | 4,076 (78.2) |
Emergency surgery | 76 (14.8) | 5 (10.6) | 671 (12.9) |
Scheduled surgery | 52 (10.2) | 4 (8.5) | 466 (8.9) |
Main symptom at admission | |||
Multiple organ failure | 22 (4.3) | 2 (4.3) | 135 (2.6) |
Septic shock | 110 (21.5) | 12 (25.5) | 575 (11.0) |
Hemorrhagic shock | 14 (2.7) | 2 (4.3) | 203 (3.9) |
Cardiogenic shock | 19 (3.7) | 0 | 201 (3.9) |
Mixed or other shock | 11 (2.1) | 1 (2.1) | 114 (2.2) |
Acute respiratory failure | 155 (30.3) | 17 (36.2) | 1,191 (22.9) |
Acute renal failure | 34 (6.6) | 0 | 264 (6.1) |
Coma | 64 (12.5) | 7 (14.9) | 956 (18.3) |
Chronic illness | |||
Hepatic | 40 (7.8) | 7 (14.9) | 326 (6.3) |
Cardiovascular | 60 (11.7) | 7 (14.9) | 675 (13.0) |
Pulmonary | 67 (13.1) | 7 (14.9) | 797 (15.3) |
Renal | 20 (3.9) | 5 (10.6) | 304 (5.8) |
Immunosuppression | 91 (17.8) | 6 (12.8) | 631 (12.1) |
Diabetes mellitus | 57 (11.1) | 7 (14.9) | 782 (15.0) |
LOD | 6 (4 to 8) | 7 (5 to 9) | 5 (3 to 7) |
SOFA | 8 (5.5 to 11) | 8 (6 to 12) | 6 (3 to 9) |
SAPS II | 45 (36 to 59) | 50 (39 to 63) | 39 (28 to 54) |
Duration of Mechanical ventilation | 12 (3 to 26) | 14(8 to 29) | 1 (0 to 6) |
Duration of Proton pump inhibitor | 12 (5 to 25) | 15(9 to 30) | 3 (0 to 7) |
McCabe score | |||
Unplanned death in five years | 292 (57) | 32 (68.1) | 3,047 (58.5) |
Planned death between one and five years | 184 (35.9) | 12 (25.5) | 1,697 (32.6) |
Planned death in a year | 36 (7) | 3 (6.4) | 459 (8.8) |
Prognosis | |||
Death during ICU stay | 128 (25) | 10 (21.3) | 1,115 (21.4) |
Death during hospital stay | 173 (33.8) | 16 (34) | 1,396 (26.8) |
Duration of ICU stay | 17 (8 to 33.5) | 20 (12 to 42) | 4 (3 to 9) |
Duration of hospital stay | 40 (23 to 67) | 46 (28 to 78) | 19 (9 to 36) |