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Table 3 Clinical characteristics of the interleukin-27 cohort

From: Interleukin-27 is a novel candidate diagnostic biomarker for bacterial infection in critically ill children

 

Controls (n= 61)

SIRS (n= 101)

Sepsis (n= 38)

Septic shock (n= 92)

Median age in years

4.3 (1.2-6.5)

3.8 (1.2-6.4)

1.3 (0.4-5.3)a

2.4 (0.9-5.8)

Males (%)

57

58

58

64

Median PRISM score

-

7 (2-11)

7 (5-13)

14 (8-21)b

Mortality (%)

-

0

5

14c

Median IL-27 (ng/ml)

1.0 (0.7-1.6)d

2.5 (1.6-3.7)e

6.1 (3.6-9.5)

5.9 (3.2-10.9)

Median PCT (ng/ml)

 

1.3 (0.1-2.4)

1.8 (0.1-4.9)

6.1 (2.7-20.5)b

  1. PRISM, pediatric risk of mortality; SIRS, systemic inflammatory response syndrome. aP < 0.05 versus Controls. bP < 0.05 versus SIRS and sepsis. cP < 0.05 versus SIRS. dP < 0.05 versus SIRS, sepsis, and septic shock. eP < 0.05 versus sepsis and septic shock.