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Table 7 Progression to septic shock (SS) and mortality after septic shock among patients with sepsis

From: Polymorphic variants in exon 8 at the 3' UTR of the HLA-G gene are associated with septic shock in critically ill patients

Polymorphism Outcome With IN, n (%) Without IN, n (%) P-value p corr
+2960INDEL With sepsis 363 (74.4) 153 (72.9) - -
  Progression to SS 266/363 (73.3) 98/153 (64.1) 0.046 0.414
  ICU mortality 135/266 (50.8) 51/98 (52.0) 0.920 -
  ICU + hospital mortality 162/266 (60.9) 65/98 (66.3) 0.409 -
Polymorphism Outcome With +3003C, n (%) Without +3003C, n (%) P -value  
+3003C>T With sepsis 98 (20.9) 371 (79.1) -  
  Progression to SS 71/98 (72.4) 258/371 (69.5) 0.663 -
  ICU mortality 44/71 (62.0) 126/258 (48.8) 0.068 -
  ICU + hospital mortality 50/71 (70.4) 160/258 (62.3) 0.244 -
Polymorphism Outcome With +3010C, n (%) Without +3010C, n (%) P -value  
+3010C>G With sepsis 373 (79.5) 96 (20.5) - -
  Progression to SS 267/373 (71.6) 62/96 (64.6) 0.226 -
  ICU mortality 135/267 (50.6) 35/62 (56.5) 0.487 -
  ICU + hospital mortality 166/267 (62.2) 44/62 (71.0) 0.249 -
Polymorphism Outcome With +3027A, n (%) Without +3027A, n (%) P -value  
+3027 A>C With sepsis 36 (7.7) 433 (92.3) - -
  Progression to SS 25/36 (69.4) 304/433 (70.0) 1.000 -
  ICU mortality 15/25 (60.0) 155/304 (51.0) 0.510 -
  ICU + hospital mortality 17/25 (68.0) 193/304 (63.5) 0.814 -
Polymorphism Outcome With +3035T, n (%) Without +3035T, n (%) P -value  
+3035C>T With sepsis 125 (26.7) 344 (73.3) - -
  Progression to SS 96/125 (76.8) 233/344 (67.7) 0.075 -
  ICU mortality 51/96 (53.1) 119/233 (51.1) 0.828 -
  ICU + hospital mortality 63/96 (65.6) 147/233 (63.1) 0.757 -
Polymorphism Outcome With +3142G, n (%) Without +3142G, n (%) P -value  
+3142C>G With sepsis 431 (83.5) 85 (16.5) - -
  Progression to SS 309/431 (71.7) 55/85 (64.7) 0.245 -
  ICU mortality 157/309 (50.8) 29/55 (52.7) 0.908 -
  ICU + hospital mortality 188/309 (60.8) 39/55 (70.9) 0.204 -
Polymorphism Outcome With +3187ª, n (%) Without +3187ª, n (%) P -value  
+3187A>G With sepsis 447 (95.3) 22 (4.7) - -
  Progression to SS 316/447 (70.7) 13/22 (59.1) 0.356 -
  ICU mortality 162/316 (51.3) 8/13 (61.5) 0.658 -
  ICU + hospital mortality 200/316 (63.3) 10/13 (76.9) 0.479 -
  1. P-value, chi square test; Pcorr, P-value after Bonferroni correction (n = 9).