Table 1 Respiratory effect of acute lung injury (ALI) and different levels of positive end-expiratory pressures (PEEP) at different levels of intra-abdominal pressures (IAP).
Before ALI | After ALI | ||||||||
|---|---|---|---|---|---|---|---|---|---|
PEEP cmH2O (mmHg) | Baseline | Baseline | High | Baseline | Moderate | High | Baseline | Moderate | High |
5 (3.7) | 5 (3.7) | 15 (11.0) | 5 (3.7) | 12 (8.8) | 25 (18.4) | 5 (3.7) | 15 (11.0) | 30 (21.1) | |
IAP cmH2O (mmHg) | Baseline | Baseline | Baseline | Grade II IAH | Grade II IAH | Grade II IAH | Grade III IAH | Grade III IAH | Grade III IAH |
5.9 (4) | 5.9 (4) | 5.9 (4) | 24.5 (18) | 24.5 (18) | 24.5 (18) | 29.9 (22) | 29.9 (22) | 29.9 (22) | |
PEEP measured, cmH2O | 6 (0.2) | 7 (0.3) | 17 (0.4) | 7 (0.2) | 14 (0.2) | 27 (0.3) | 6 (0.4) | 17 (0.3) | 32 (0.3) |
PAW EI, cmH2O | 17 (1) | 20 (4)b | 32 (4)c | 32 (6)a | 37 (5)d | 48 (3)e,f | 34 (6)a | 40 (4)d | 54 (3)e,f |
PES EE, cmH2O | 7 (3) | 8 (2) | 10 (2)c | 8 (2) | 11 (2)d | 17 (6)e,f | 8 (2) | 13 (4)d | 18 (7)e,f |
PES EI, cmH2O | 10 (2) | 12 (2) | 14 (3) | 18 (6)a | 20 (7) | 24 (11)f | 19 (6)a | 21 (8) | 23 (11) |
PTP EE, cmH2O | -1 (3) | -1 (2) | 7 (2)c | -1 (2) | 3 (3)d | 10 (6)e,f | -2 (1) | 4 (4)d | 14 (7)e,f |
PTP EI, cmH2O | 7 (2) | 8 (4)b | 18 (6)c | 15 (7)a | 18 (9) | 24 (12)e,f | 16 (9)a | 20 (10) | 30 (13)e,f |
PTD EE, cmH2O | 0 (5) | 2 (6) | 0 (4) | 17 (1)a | 13 (3)d | 8 (5)e,f | 19 (3)a | 13 (4)d | 11 (7)e |
PTD EI, cmH2O | -1 (4) | -1 (6) | -2 (4) | 10 (4)a | 9 (6) | 10 (9) | 10 (7)a | 10 (7) | 13 (11) |
ECW, cmH2O/L | 8 (2) | 9 (3) | 8 (4) | 25 (10)a | 19 (9)d | 17 (11)e,f | 29 (11)a | 19 (12)d | 14 (13)e |
EL, cmH2O/L | 20 (2) | 23 (6) | 27 (8) | 37 (12)a | 34 (12) | 32 (10) | 38 (14)a | 34 (9) | 37 (12) |
PaCO2, mmHg | 44 (2) | 52 (4)b | 50 (6) | 60 (6)a | 58 (6) | 52 (5)e,f | 59 (4)a | 56 (4) | 51 (8)e,f |