Table 1 Parameters of the studied patients
From: Toll-like receptors expression and interferon-γ production by NK cells in human sepsis
Parameter | SIRS (n= 11) | Sepsis (n= 27) |
|---|---|---|
Age, y, mean (SD) | 59.7 (21.0) | 70.6 (14.9) |
Gender, n (%) | ||
Male | 10 (90.9%) | 14 (51.8%) |
Female | 1 (9.1%) | 13 (48.2%) |
Body mass index, Kg/m2, mean (SD) | 26.2 (6.2) | 26.9 (7.2) |
Comorbidity, n (%) | ||
Heart failure | 0 (0%) | 1 (3.7%) |
Ischemic cardiopathy | 1 (9.1%) | 7 (25.9%) |
COPD | 3 (27.3%) | 4 (14.8%) |
Chronic renal failure | 1 (9.1%) | 3 (11.1%) |
Liver failure | 0 (0%) | 1 (3.7%) |
Diabetes | 1 (9.1%) | 6 (22.2%) |
Cancer | 2 (18.2%) | 5 (18.5%) |
Infection site | ||
Lung | NA | 17 (62.9%) |
Abdominal | NA | 7 (25.9%) |
Urinary tract | NA | 2 (7.4%) |
Positive blood culture | NA | 7 (25.9%) (among these, one had primitive bacteremia) |
Temperature, °C, mean (SD) | 38.2 (2.0) | 37.8 (2.1) |
Heart rate, bpm, mean (SD) | 127 (23) | 121.9 (18.7) |
Mean blood pressure, mmHg, mean (SD) | 72.9 (19.7) | 65.2 (23) |
Respiratory rate, c/min, mean (SD) | 29.8 (14.4) | 30.1 (8.2) |
Leukocytes, 10E9/L, mean (SD) | 12.9 (4.4) | 15.08 (8.4) |
SOFA, mean (SD) | 8.3 (3.4) | 9.1 (4.1) |
SAPS II, mean (SD) | 41.4 (17.5) | 48.3 (21.3) |
McCABE classification (underlying diseases) | ||
Category 1, number (%) | 10 (90.9%) | 22 (81.5%) |
Category 2, number (%) | 1 (9.1%) | 4 (14.8%) |
Category 3, number (%) | 0 (0%) | 1(3.7%) |
Length of stay in hospital, days, mean (SD) | 30.0 (35.2) | 40.2 (42.0) |
Length of stay in ICU, days, mean (SD) | 11.4 (10.6) | 24.1 (33.6) |
In-hospital mortality, number (%) | 3 (27.3%) | 12 (44.4%) |
Microbes, number patients Gram-positive bacteria | NA | 12 (among these two had Gram-positive anaerobes) |
Gram-negative bacteria | NA | 19 |
Mycobacterium spp. | NA | 1 |
Fungus | NA | 1 |
Undetermined microbial infection | 1 (polymicrobial flora) |