Figure 2
From: Toll-like receptors expression and interferon-γ production by NK cells in human sepsis
Analysis of the expression of Toll-like receptor 2 (TLR2) by flow cytometry in natural killer (NK) cell CD56bright and CD56dim subsets. (A) Representative flow cytometry histogram of surface expression of TLR2 on CD56bright and CD56dim NK cell subsets for healthy volunteers, systemic inflammatory response syndrome (SIRS), and sepsis patients. Black line: isotype control; colored line: anti-TLR2. (B) Surface TLR2 expression shown as median and interquartile range in all three studied groups. (C) Representative flow cytometry histogram of intracellular expression of TLR2 for the same samples represented in (A). Black line: isotype control; colored line: anti-TLR2. (D) Intracellular TLR2 expression shown as median and interquartile range in all three studied groups. **P < 0.01 for comparison with healthy controls. MFI, mean fluorescence intensity.