Table 2 Impedance aggregometry findings, sepsis markers, ICU-scores, and coagulation variables in postoperative and septic patients.
From: Whole blood impedance aggregometry as a biomarker for the diagnosis and prognosis of severe sepsis
Testnormal range | Postop. patients mean and SEM median (quartiles) | Patients with sepsis mean and SEM median (quartiles) | Significance levelMann-Whitney-test |
|---|---|---|---|
Aggregometry | |||
ADP-test 53 - 122 AU | 55.66 ± 3.80 52.85 (36.7, 76.00) | 31.87 ± 3.50 23.70 (8.30, 42.68) | <0.001 |
AA-test 74 - 136 AU | 78.08 ± 5.71 72.40 (41.78, 111.75) | 54.65 ± 4.81 41.10 (18.30, 87.72) | 0.001 |
Col-test 46 - 116 AU | 68.13 ± 4.18 70.75 (44.38, 83.22) | 35.28 ± 3.52 26.75 (12.73, 45.75) | <0.001 |
TRAP-test 94 - 156 AU | 83.52 ± 4.38 77.30 (60.10, 108.65) | 58.20 ± 4.38 47.55 (25.08, 89.45) | <0.001 |
Sepsis marker | |||
Procalcitonin 0 - 0.5 ng/ml | 2.09 ± 0.41 1.2 (0.44, 2.60) | 18.87 ± 5.13 4.55 (1.45, 17.60) | <0.001 |
IL 6 0 - 3.4 pg/ml | 297.11 ± 40.95 181.50 (83.50, 439.50) | 788.97 ± 310.20 95.85 (40.75, 401.50) | 0.045 |
CRP 0 - 0.5 mg/dl | 12.18 ± 0.81 13.20 (8.55, 16.05) | 13.79 ± 1.02 13.10 (6.13, 18.58) | 0.813 |
ICU-Scores | |||
SAPSII | 21.4 ± 9.4 22.0 (15.5, 29.0) | 48.9 ± 17.1 51.0 (36.0, 65.0) | <0.001 |
SOFA | 3.4 ± 2.5 4.0 (1.0, 6.0) | 11.6 ± 4.6 12.0 (8.0, 15.0) | <0.001 |
Coagulation variables | |||
INR 0.89 - 1.11 | 1.19 ± 0.02 1.17 (1.08, 1.29) | 1.38 ± 0.06 1.27 (1.11, 1.48) | 0.029 |
Thrombin time 14 - 21 s | 18.1 ± 0.7 17.0 (15.8, 19.1) | 23.9 ± 1.7 18.6 (15.3, 24.8) | 0.105 |
Fibrinogen 210 - 400 mg/dl | 406 ± 27 364 (312, 495) | 479 ±30 471 (240, 662) | 0.285 |
Platelets 160 - 350/nl | 207 ± 14 196 (154, 245) | 137 ± 12 107 (57, 187) | <0.001 |