A comparison of RIFLE with and without urine output criteria for acute kidney injury in critically ill patients

Table 2 Baseline characteristics

Variables	All (n= 260)	Known pre-ICUadmission SCr (n= 101)	Unknown pre-ICU admission SCr (n= 159)	P-value
Age (years)	60 ± 16	64 ± 13	58 ± 17	<0.01
Men (%)	62	65	60	NS
Weight (kg)	83 ± 22	81 ± 22	84 ± 22	NS
APACHE II	21 ± 8	21 ± 7	21 ± 9	NS
SAPS	52 ± 17	54 ± 16	50 ± 17	NS
Type of admission (%)
Medical	56	50	61	NS
Surgical urgent	27	22	30	NS
Surgical elective	17	28	9	<0.01
Baseline SCr (μmol/l)
Pre-ICU admission	-	90 ± 34	unknown
Admission	115 ± 93	125 ± 121	107 ± 69	NS
Estimated²⁾	88 ± 12	88 ± 12	88 ± 13	NS
ICU mortality (%)	21	19	22	NS
ICU stay (days)	7.0 (5.0 to 12.0)	7.0 (4.25 to 10.75)	8.0 (5.0 to 13.5)	NS
Comorbidity (%)
Hypertension	30	34	27	NS
Diabetes mellitus	17	22	14	NS
Chronic Renal Failure¹⁾	6	10	4	NS
Cardiovascular disease	33	39	30	NS

Values are mean ± SD, median (quartiles) or percentage of patients. APACHE, Acute Physiology and Chronic Health Evaluation; GFR, glomerular filtration rate; SAPS, Simplified Acute Physiology Score; SCr, serum creatinine. ¹⁾ GFR <45 ml/min, based on pre-ICU admission morbid SCr and MDRD equation [4]. ²⁾ Based on the MDRD equation assuming a GFR of 75 ml/min/1.73 m² [4].

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