From: Candida score: a predictor of mortality in patients with candidemia
Parameter of interest | Overall (n= 56) | Survivors (n= 37) | Nonsurvivors (n= 19) | P value |
---|---|---|---|---|
Age, mean | 63.07 ± 20.7 | 59.11 ± 21.9 | 70.79 ± 16.1 | 0.045* |
Sex, males (%) | 41 (73.2%) | 27 (73%) | 14 (73.7%) | 0.955 |
APACHE II score | 19.38 ± 7.7 | 17.32 ± 7.6 | 23.37 ± 6.2 | 0.004* |
Predicted death rate (%) | 36.87 ± 22.6 | 31.05 ± 21.7 | 48.19 ± 20.2 | 0.006* |
Nonalbicans infection | 44 (78.6%) | 31 (83.8%) | 13 (68.4%) | 0.302 |
Co-existing candiduria | 15 (26.8%) | 10 (27%) | 5 (26.3%) | 0.955 |
Underlying co-morbidities | 41 (73.2%) | 24 (64.9%) | 18 (94.7%) | 0.021* |
Previous antimicrobials | 49 (87.5%) | 33 (89.2%) | 16 (84.2%) | 0.679 |
Previous antifungals | 8 (14.3%) | 1 (0.3%) | 7 (36.8%) | 0.001* |
Days in ICU before positive culture | 12.88 ± 14.4 | 13.05 ± 14.6 | 12.53 ± 14.3 | 0.898 |
Recent hospitalization | 17 (30.4%) | 11 (29.7%) | 6 (31.6%) | 0.887 |
Total parenteral nutrition | 18 (32.1%) | 15 (40.5%) | 3 (15.8%) | 0.076 |
Candida score (≥3) | 29 (51.8%) | 15 (40.5%) | 14 (73.7%) | 0.025* |
Presence of CVC | 49 (87.5%) | 31 (83.8%) | 18 (94.7%) | 0.403 |
Mechanical ventilation | 36 (64.3%) | 19 (51.4%) | 17 (89.5%) | 0.007* |
Vasopressor support | 30 (53.6%) | 13 (35.1%) | 17 (89.5%) | 0.000* |
Renal replacement therapy | 23 (41.1%) | 9 (24.3%) | 14 (73.7%) | 0.001* |
Length of ICU stay (days) | 22.86 ± 28 | 22.35 ± 31.4 | 23.84 ± 20.6 | 0.853 |
Length of hospital stay (days) | 30.09 ± 30.2 | 33.19 ± 33.8 | 24.05 ± 21.1 | 0.288 |