Table 2 Quality indicators and assessment of risk of bias in the included randomized controlled trials
Quality indicators/studies | Shaw and colleagues[23] | Vajkoczy and colleagues[24] | CONSCIOUS-1[25] | CONSCIOUS-2[16] | CONSCIOUS-3[26] |
|---|---|---|---|---|---|
Randomized controlled study | Yes | Yes | Yes | Yes | Yes |
Appropriate random sequence generation | Yes | Unclear | Unclear | Yes | Yes |
Allocation concealment | Unclear | Unclear | Unclear | Yes | Yes |
Blinding of participants and personnel | Yes | Yes | Yes | Yes | Yes |
Blinding of outcome assessment | Unclear | Yes | Yes | Yes | Yes |
Explanation for withdrawals and dropouts | No | Yes | Yes | Yes | Yes |
Jadad scale | 4 | 4 | 4 | 5 | 5 |