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Table 3 Patient characteristics and outcome of patients with or without fluid overload.

From: Fluid overload is associated with an increased risk for 90-day mortality in critically ill patients with renal replacement therapy: data from the prospective FINNAKI study

  Data
available
Fluid
overload
n= 76
No fluid
overload
n= 207
P value
Age (years) 283 64 [53-74] 64 [55-73] 0.934
Male gender 283 48 [63.2] 142 [68.6] 0.395
Baseline weight (kg) 283 75 [68-88] 83 [70-98] 0.004
Baseline creatinine (umol/L) 195 79 [68-99] 88 [70-126] 0.043
Emergency admission 279 67 (89.3) 192 (94.1) 0.192
Surgical admission 282 27 (35.5) 62 (30.1) 0.390
SAPS II score 283 55 [44-77] 50 [40-63] 0.025
SAPS II score without age points 283 44 [33-62] 40 [28-51] 0.016
Severe sepsis (during ICU stay) 283 49 (64.5) 88 (42.5) 0.001
Vasoactives (during ICU stay) 283 71 (93.4) 167 (80.7) 0.010
Mechanical ventilation (during ICU stay) 283 71 (93.4) 138 (66.7) < 0.001
Parameters at RRT initiation     
SOFA score on RRT initiation day 277 11 [8-14] 10 [7-12] 0.002
Renal SOFA score on RRT initiation day 277 4 [3-4] 3 [2-4] 0.041
Cumulative balance on RRT initiation day (L) 283 10.5 [9.0-13.2] 2.4 [0.2-4.6] < 0.001
Fluid accumulation on RRT initiation day (%) 283 13.1 [11.3-18.6] 3.0 [0.2-5.7] < 0.001
Urine output mL/24 hr on RRT initiation day 265 164 [35-511] 429 [110-1531] < 0.001
Received diuretics prior to RRT initiation 283 54 (71.1) 137 (66.2) 0.477
Received colloids prior to RRT initiation 278 69 (90.8) 131 (64.9) < 0.001
Amount of colloids received on ICU prior to RRT initiation (mL) 281 1500 [564-2500] 400 [0-1000] < 0.001
Creatinine prior to RRT initiation (umol/L) 279 206 [140-320] 281 [180-493] 0.001
Lactate prior to RRT initiation (mmol/L) 263 3.9 [1.8-7.2] 2.1 [1.2-6.0] 0.011
pH prior to RRT initiation 280 7.28 [7.18-7.38] 7.29 [7.18-7.38] 0.701
Base excess prior to RRT initiation (mmol/L) 281 -9.3 [-13.2- -4.3] -8.6 [-14.4 - -4.0] 0.904
Time from ICU admission to RRT initiation (hours) 278 26.9 [10.7-43.7] 9.3 [2.5-35.7] < 0.001
CRRT as initial modality 283 70 (92.1) 138 (66.7) < 0.001
Length of stay (days)     
ICU 283 6.5 [2.2-15.0] 4.8 [2.1-9.9] 0.144
Hospital 281 12.5 [2.0-26.0] 15.0 [2.0-26.0] 0.037
Crude mortality     
Hospital 283 43 (56.6) 49 (23.7) < 0.001
By day 90 283 45 (59.2) 65 (31.4) < 0.001
Dependent on RRT at 90 days (of survivors) 162 3 (10.7) 31 (23.1) 0.202
  1. Continuous variables expressed as median [interquartile range]. Nominal variables expressed as number (%). ICU, intensive care unit; SAPS, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment.