Table 3 Patient characteristics and outcome of patients with or without fluid overload.

Age (years)

283

64 [53-74]

64 [55-73]

0.934

Male gender

283

48 [63.2]

142 [68.6]

0.395

Baseline weight (kg)

283

75 [68-88]

83 [70-98]

0.004

Baseline creatinine (umol/L)

195

79 [68-99]

88 [70-126]

0.043

Emergency admission

279

67 (89.3)

192 (94.1)

0.192

Surgical admission

282

27 (35.5)

62 (30.1)

0.390

SAPS II score

283

55 [44-77]

50 [40-63]

0.025

SAPS II score without age points

283

44 [33-62]

40 [28-51]

0.016

Severe sepsis (during ICU stay)

283

49 (64.5)

88 (42.5)

0.001

Vasoactives (during ICU stay)

283

71 (93.4)

167 (80.7)

0.010

Mechanical ventilation (during ICU stay)

283

71 (93.4)

138 (66.7)

< 0.001

Parameters at RRT initiation

SOFA score on RRT initiation day

277

11 [8-14]

10 [7-12]

0.002

Renal SOFA score on RRT initiation day

277

4 [3-4]

3 [2-4]

0.041

Cumulative balance on RRT initiation day (L)

283

10.5 [9.0-13.2]

2.4 [0.2-4.6]

< 0.001

Fluid accumulation on RRT initiation day (%)

283

13.1 [11.3-18.6]

3.0 [0.2-5.7]

< 0.001

Urine output mL/24 hr on RRT initiation day

265

164 [35-511]

429 [110-1531]

< 0.001

Received diuretics prior to RRT initiation

283

54 (71.1)

137 (66.2)

0.477

Received colloids prior to RRT initiation

278

69 (90.8)

131 (64.9)

< 0.001

Amount of colloids received on ICU prior to RRT initiation (mL)

281

1500 [564-2500]

400 [0-1000]

< 0.001

Creatinine prior to RRT initiation (umol/L)

279

206 [140-320]

281 [180-493]

0.001

Lactate prior to RRT initiation (mmol/L)

263

3.9 [1.8-7.2]

2.1 [1.2-6.0]

0.011

pH prior to RRT initiation

280

7.28 [7.18-7.38]

7.29 [7.18-7.38]

0.701

Base excess prior to RRT initiation (mmol/L)

281

-9.3 [-13.2- -4.3]

-8.6 [-14.4 - -4.0]

0.904

Time from ICU admission to RRT initiation (hours)

278

26.9 [10.7-43.7]

9.3 [2.5-35.7]

< 0.001

CRRT as initial modality

283

70 (92.1)

138 (66.7)

< 0.001

Length of stay (days)

ICU

283

6.5 [2.2-15.0]

4.8 [2.1-9.9]

0.144

Hospital

281

12.5 [2.0-26.0]

15.0 [2.0-26.0]

0.037

Crude mortality

Hospital

283

43 (56.6)

49 (23.7)

< 0.001

By day 90

283

45 (59.2)

65 (31.4)

< 0.001

Dependent on RRT at 90 days (of survivors)

162

3 (10.7)

31 (23.1)

0.202