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Table 2 Patient characteristics of all patients and compared between survivors and non-survivors.

From: Fluid overload is associated with an increased risk for 90-day mortality in critically ill patients with renal replacement therapy: data from the prospective FINNAKI study

  Data
available
All
n= 296
Survivors
n= 180
Non-survivors
n= 116
P value
Age (years) 296 64 [55-73] 62 [50-69] 70 [58-77] < 0.001
Male gender 296 197 (66.6) 121 (67.2) 76 (65.5) 0.801
Baseline weight (kg) 296 80 [70-95] 85 [70-100] 76 [69-87] 0.001
Baseline creatinine (umol/L) 202 86 [70-116] 91 [71-117] 81 [68-114] 0.201
Emergency admission 292 271 (92.8) 164 (92.7) 107 (93.0) 0.900
Surgical admission 295 94 (31.9) 59 (33.0) 35 (30.2) 0.701
SAPS II score 296 51 [40-65] 46 [36-56] 63 [51-77] < 0.001
SAPS II score without age points 296 40 [29-55] 36 [25-45] 51 [37-64] < 0.001
Severe sepsis (during ICU stay) 296 142 (48.0) 73 (40.6) 69 (59.5) 0.002
Vasoactives (during ICU stay) 296 251 (84.8) 143 (79.4) 108 (93.1) 0.001
Mechanical ventilation (during ICU stay) 296 220 (74.3) 117 (65.0) 103 (88.8) < 0.001
Parameters at RRT initiation      
SOFA score on RRT initiation day 290 10 [7-12] 9 [6-11] 12 [9-14] < 0.001
Renal SOFA score on RRT initiation day 290 3 [2-3] 3 [1-4] 4 [2-4] 0.022
Cumulative balance on RRT initiation day (L) 283 3.8 [1.3-8.3] 3.1 [0.3-6.4] 6.2 [2.2-9.7] < 0.001
Fluid accumulation on RRT initiation day (%) 283 5.1 [1.5-10.3] 3.6 [0.3-8.2] 8.0 [3.0-12.9] < 0.001
Urine output mL/24 hr on RRT initiation day 278 325 [80-1191] 510 [157-1701] 150 [35-496] < 0.001
Received diuretics prior to RRT initiation 296 202 (68.2) 117 (65.0) 85 (73.3) 0.160
Received colloids prior to RRT initiation 290 208 (71.7) 114 (64.4) 94 (83.2) < 0.001
Amount of colloids received on ICU prior to RRT initiation (mL) 291 500 [0-1500] 500 [0-1250] 976 [138-2000] 0.001
Creatinine prior to RRT initiation (umol/L) 290 261 [168-427] 279 [169-506] 237 [164-336] 0.049
Lactate prior to RRT initiation (mmol/L) 276 2.4 [1.2-6.0] 1.8 [1.1-4.8] 3.8 [1.7-8.0] < 0.001
pH prior to RRT initiation 291 7.29 [7.18-7.38] 7.31 [7.20-7.38] 7.25 [7.17-7.37] 0.072
Base excess prior to RRT initiation (mmol/L) 292 -8.8 [-13.6- -4.0] -7.6 [-13.0- -3.4] -10.0 [-13.9- -5.1] 0.046
Time from ICU admission to RRT initiation (hours) 290 14.0 [3.3-41.5] 10.9 [2.5-42.1] 19.2 [6.3-41.3] 0.039
CRRT as initial modality 296 215 (72.6) 121 (67.2) 94 (81.0) 0.011
Length of stay (days)      
ICU 296 5.5 [2.2-10.9] 6.0 [2.8-11.6] 4.0 [1.8-9.9] 0.039
Hospital 294 14.5 [6.0-27.3] 20.0 [11.0-32.0] 6.0 [2.0-18.0] < 0.001
  1. Continuous variables expressed as median [interquartile range]. Nominal variables expressed as number (%). ICU, intensive care unit; RRT, renal replacement therapy; SAPS, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment.