Investigating risk factors for psychological morbidity three months after intensive care: a prospective cohort study

Table 7 Final multiple regression models of strongest* risk factors for post-ICU anxiety at three months

	R² Cumulative variance explained	Socio-demographic, clinical and chronic physical factors† (column 1)		Socio-demographic, clinical, chronic physical and acute psychological factors (column 2)		Socio-demographic, clinical, chronic health, acute psychological and psychological history (column 3)
		Unstandardised coefficients (95% CI)	P	Unstandardised coefficients (95% CI)	P	Unstandardised coefficients (95% CI)	P
SEC2‡		11.52 (1.50, 21.55)	<0.05	7.82 (-2.47, 18.10)	0.13	9.35 (-0.81, 19.52)	0.07
SEC3		5.87 (-2.06, 13.80)	0.15	5.92 (-1.84, 13.68)	0.13	4.73 (-2.94, 12.41)	0.22
SEC4		-2.17 (-13.37, 9.03)	0.70	-2.45 (-13.41, 8.51)	0.66	-1.37 (-12.15, 9.40)	0.80
SEC5		7.81 (-0.08, 15.7)	<0.05	8.14 (0.223, 16.05)	<0.05	7.99 (0.24, 15.73)	<0.05
SEC6		10.66 (0.37, 20.94)	<0.05	9.57 (-0.69, 19.82)	0.07	9.76 (-0.29, 19.80)	0.06
Inotropes or vasopressors (yes/no)		6.60 (0.67, 12.53)	<0.05	5.48 (-0.46, 11.42)	0.07	4.64 (-1.23, 10.50)	0.12
Benzodiazepines (yes/no)		4.06 (-1.87, 9.99)	0.18	2.59 (-3.34, 8.52)	0.39	2.08 (-3.74, 7.90)	0.48
Chronic physical health (yes/no)		6.57 (0.95, 12.12)	<0.05	4.62 (-1.14, 10.37)	0 .1	5.16 (-0.50, 10.81)	0.07
	0.25 (25%)
Mood				0.26 (0.04, 0.49)	<0.05	0.20 (-0.03, 0.428)	0.09
Timeline (BIPQ)				0.36 (-0.70, 1.43)	0.50	0.18 (-0.87, 1.24)	0.73
	0.30 (30%)
Psychological history (yes/no)						8.37 (0.67, 16.08)	<0.05
	0.34 (34%)

Anxiety was measured using the State-trait anxiety inventory (STAI), range of scores 0 to 80
* Strongest risk factors were identified in a previous univariable analysis, followed by multivariable analysis of each group of risk factors (socio-demographic, clinical, acute psychological, chronic health).
† Factors were entered in this final multiple regression in the following order: 1. Socio-demographic 2. Clinical 3. Chronic physical conditions 4. Acute psychological 5. Psychological history (each stage is not shown in a separate column for space reasons)
‡ Variables SEC2-SEC6 are dummy variables representing differences between occupational categories within the National Statistics Socio-economic classification (NS-SEC). In each dummy variable the numbered category is compared with the baseline of category 1. (NS-SEC categories are: 1. Professions/managerial 2. Intermediate professions 3. Self-employed 4. Technical/craft 5. Semi-routine/routine 6. Unclassified)

ISSN: 1364-8535