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Table 2 Outcome data of studies included in the meta-analysis of toothbrushing for ventilator-associated pneumonia prevention (intervention versus control)

From: Impact of oral care with versus without toothbrushing on the prevention of ventilator-associated pneumonia: a systematic review and meta-analysis of randomized controlled trials

Study

Primary outcome

Secondary outcomes

 

Incidence of VAP

ICU mortality

Length of ICU stay, days

Duration of MV, days

Antibiotic-free day, days

MV-free day, days

Munro et al. [20] (2009)

48/97 vs. 45/95

22/97 vs. 22/95

NR

NR

NR

NR

Pobo et al. [21] (2009)

15/74 vs. 18/73

16/74 vs. 23/73

12.9 ± 8.7 vs. 15.5 ± 9.6

8.9 ± 5.8 vs. 9.8 ± 6.1

7.6 ± 8.4 vs. 7.8 ± 7.6

9.5 ± 12.2 vs. 11.3 ± 12.3

Yao et al. [22] (2011)

4/28 vs. 14/25

NR

12.5 ± 6.1 vs. 13.5 ± 6.8

12.0 ± 11.0 vs. 13.6 ± 15.6

NR

NR

Lorente et al. [23] (2012)

21/217 vs. 24/219

62/217 vs. 69/219

12.07 ± 15.55 vs. 13.04 ± 17.27

9.18 ± 14.13 vs. 9.93 ± 15.39

7.43 ± 14.84 vs. 8.39 ± 16.83

4.03 ± 3.22 vs. 4.42 ± 3.93

  1. ICU, intensive care unit; MV, mechanical ventilation; NR, not reported; VAP, ventilator-associated pneumonia.