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Table 2 Description of bleeding sites (n = 686)

From: Reversal of Vitamin K Antagonist (VKA) effect in patients with severe bleeding: a French multicenter observational study (Optiplex) assessing the use of Prothrombin Complex Concentrate (PCC) in current clinical practice

Site Number (percentage)
Intracranial 300 (43.7)
Gastrointestinal 167 (24.3)
Deep muscle hematoma or neural compression syndrome or both 65 (9.5)
Hemoperitoneum/Hemoretroperitoneum 59 (8.6)
Hemothorax 26 (3.8)
Hematuria 22 (3.2)
Hemoptysis 17 (2.5)
Hemopericardium 6 (0.9)
Hemarthrosis 6 (0.9)
Intraocular or retro-orbital 4 (0.6)
Intraspinal 2 (0.3)
Unknown 37 (5.4)
  1. Multiple sites of bleeding were observed in several patients: 22 patients with two sites, four patients with three sites, and one patient with four sites.