Table 1 Pathway analysis using the gene signature discovered during the identification of sepsis subtypes
From: Identification of sepsis subtypes in critically ill adults using gene expression profiling
Pathway | P-value | Bonferonni |
|---|---|---|
Inflammation mediated by chemokine and cytokine signaling pathway | 2.70E-08 | 0.0000048 |
Toll receptor signaling pathway | 7.66E-05 | 0.0135 |
T cell activation | 4.75E-03 | 0.835 |
p38 MAPK pathway | 5.38E-03 | 0.946 |
JAK/STAT signaling pathway | 7.59E-03 | 1 |
Beta3 adrenergic receptor signaling pathway | 0.02 | 1 |
Integrin signalling pathway | 0.02 | 1 |
B cell activation | 0.02 | 1 |
Interferon-gamma signaling pathway | 0.02 | 1 |
Opioid prodynorphin pathway | 0.02 | 1 |
Opioid proenkephalin pathway | 0.02 | 1 |
5HT4 type receptor mediated signaling pathway | 0.02 | 1 |
Opioid proopiomelanocortin pathway | 0.03 | 1 |
Salvage pyrimidine deoxyribonucleotides | 0.03 | 1 |
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | 0.04 | 1 |
Nicotinic acetylcholine receptor signaling pathway | 0.04 | 1 |
Parkinson disease | 0.04 | 1 |
Beta2 adrenergic receptor signaling pathway | 0.04 | 1 |
Beta1 adrenergic receptor signaling pathway | 0.04 | 1 |
5HT1 type receptor mediated signaling pathway | 0.04 | 1 |