Figure 3
From: Angiopoietin-1 variant reduces LPS-induced microvascular dysfunction in a murine model of sepsis
MAT.Ang-1 reduces the inflammatory response in sepsis. Cytokine, chemokine and growth factor levels detected at 24 hours in skeletal muscle from control, lipopolysaccharide (LPS)-treated, LPS + matrilin-1-angiopoietin-1 (MAT-Ang1)-treated and MAT.Ang1-treated groups. Data expressed as mean ± standard error of the mean of fold-change from control (n = 3 different experiments performed in duplicate). *P < 0.05, **P < 0.01 vs. control. #P < 0.05 vs. LPS. G-CSF, granulocyte colony-stimulating factor; IL-1RA, IL-1 receptor antagonist; MCP-1, monocyte chemotactic protein-1; sICAM, soluble intracellular adhesion molecule-1; TREM-1, triggering receptor expressed on myeloid cells-1.